Results 121 to 130 of about 1,114,098 (265)

FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes

FEBS Open Bio, EarlyView.
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang, Wenhui Yu, Cui Dang, Jingjing Zhang, Jiahan Lu, Jing Xue   +5 more
wiley   +1 more source

Comparison of three-dimensional cell culture techniques of dedifferentiated liposarcoma and their integration with future research. [PDF]

Front Cell Dev Biol
Tahara S, Sharma S, de Faria FCC, Sarchet P, Tomasello L, Rentsch S, Karna R, Calore F, Pollock RE.   +8 more
europepmc   +1 more source

GDP‐fucose transporter SLC35C1: a potential regulatory role in cytosolic GDP‐fucose and fucosylated glycan synthesis

FEBS Open Bio, EarlyView.
The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

Aging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

Monte Carlo modeling of radiation dose from radiation therapy with superficial x‐rays

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Introduction Superficial x‐rays (50–100 kVp) are used for treating non‐melanoma skin cancer and intraoperative radiation therapy (IORT). At these energies, the photoelectric effect significantly increases absorbed dose to bone compared to soft tissue.
Reham Barghash, Tiffany W. Martin, Amber R. Prebble, Del Leary   +3 more
wiley   +1 more source

AAPM Task Group No. 249.B—Essentials and guidelines for clinical medical physics residency training program

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract The establishment of guidelines and curriculum standards for medical physics residency training is a critical component of setting expectations and competencies for the profession. Since the last publication of these standards, residency training has become integrated into the eligibility criteria for most medical physics certification bodies.
Jonathon A. Nye, Joseph P. Dugas, William D. Erwin, David P. Gierga, Darryl G. Kaurin, Stephanie M. Leon, Ho‐Ling Anthony Liu, Zheng Feng Lu, Alphonso W. Magri, Lynn N. Rill, Leah K. Schubert, Beth A. Schueler, Irina Vergalasova, John Vetter, Brian D. Wichman, Amy Shu‐Jung Yu, Dandan Zheng   +16 more
wiley   +1 more source

Advancements in vaginal microbiota, <i>Trichomonas vaginalis</i>, and vaginal cell interactions: Insights from co-culture assays. [PDF]

Microb Cell
Cardoso FG, Tasca T.
europepmc   +1 more source

Empowering young minds through STEM education: Engaging high schoolers in Ghana through medical physics

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To promote diversity in Science, Technology, Engineering, and Mathematics (STEM), an educational presentation and hands‐on session was organised to raise awareness of STEM career opportunities among high school girls to introduce the students to the field of medical physics. Materials and Methods The study involved 65 first‐year Senior
Afua A. Yorke, Mercy T. Schandorf, Abigail N. M. Quaye, Peniel Tenkorama Twum, Bishwambhar Sengupta, Kwadwo Nkansah‐Poku, Juliana A. Kplorfia, Jessica Fagestrom   +7 more
wiley   +1 more source

Mangrove-Crab Blood Cells Proliferate In Vitro and Display Neuronal Proteins Following Pituitary-Extract Stimulus. [PDF]

Dev Neurobiol
Wajsenzon IJR, Abreu IS, Gomes CABA, Silva WABD, Biancalana A, Giestal-de-Araujo E, Allodi S.   +6 more
europepmc   +1 more source