Results 121 to 130 of about 13,847,003 (252)

Isolation and characterization of a human cementocyte-like cell line, HCY-23

Brazilian Oral Research
Cementum is the mineralized tissue covering the tooth root that functions in tooth attachment and post-eruptive adjustment of tooth position. It has been reported to be highly similar to bone in several respects but remains poorly understood in terms of ...
Amanda Bandeira de ALMEIDA, Elis Janaína Lira dos SANTOS, Gabriel Flores ABUNA, Cristiane Salmon RIBEIRO, Márcio Zaffalon CASATI, Karina Gonzales Silvério RUIZ, Francisco Humberto NOCITI JUNIOR   +6 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

THREE-DIMENSIONAL MICROFLUIDIC CELL CULTURE OF STEM CELL-DERIVED NEURONAL MODELS OF PARKINSON'S DISEASE

, 2016
Cell culture models in 3D have become an essential tool for the implementation of cellular models of neurodegenerative diseases. Parkinson’s disease (PD) is characterized by the loss of dopaminergic neurons from the substantia nigra.
LUCUMI-MORENO, Edinson
core   +1 more source

Cytotoxicity and biocompatibility of a new bioceramic endodontic sealer containing calcium hydroxide

Brazilian Oral Research
: This study evaluated the cytotoxicity and biocompatibility of a new bioceramic endodontic sealer (i.e., Sealer Plus BC) in comparison with those of MTA Fillapex and AH Plus.
Francine Benetti, Índia Olinta de Azevedo Queiroz, Pedro Henrique Chaves de Oliveira, Leticia Citelli Conti, Mariane Maffei Azuma, Sandra Helena Penha de Oliveira, Luciano Tavares Angelo Cintra   +6 more
doaj   +1 more source

Culture of Parathyroid Cells

, 2011
The parathyroid cells are highly differentiated with more or less their only function to secrete parathyroid hormone in response to the extracellular calcium level.
Per Hellman, Peyman Björklund, Hellman, Per,, Björklund, Peyman,   +3 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Comparison of biophysical properties characterized for microtissues cultured using microencapsulation and liquid crystal based 3D cell culture techniques. [PDF]

Cytotechnology, 2018
Soon CF, Tee KS, Wong SC, Nayan N, Sargunan Sundra, Ahmad MK, Sefat F, Sultana N, Youseffi M.   +8 more
europepmc   +1 more source

Establishment of an in vitro co-infection model of Cryptosporidium parvum and Giardia duodenalis

Parasites & Vectors
Background The two intestinal protozoan parasites Giardia duodenalis and Cryptosporidium parvum cause infections in a wide spectrum of vertebrates and have also been shown to infect suitable hosts simultaneously.
Manuela Kirchner, Arwid Daugschies, Cora Delling   +2 more
doaj   +1 more source