An innovative course-based undergraduate research experience (CURE) in HPV-associated cervical cancer: integrating molecular oncology research and scientific writing in undergraduate education. [PDF]
Baba SK +4 more
europepmc +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Engineering exosomes in the treatment of sensorineural hearing loss: from basic research to clinical applications. [PDF]
Wang S +7 more
europepmc +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Advanced glucose control strategies leveraging Raman spectroscopy for optimized mammalian cell culture manufacturing. [PDF]
Banner M +12 more
europepmc +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Challenges and opportunities in generating microvasculature using bioprinting techniques. [PDF]
Yu J, Murata D, Itoh M, Nakayama K.
europepmc +1 more source
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
Human iPSC-Derived Brain Organoids: A Disease-Oriented Evaluation of Modeling Fidelity. [PDF]
Pokharel BR +6 more
europepmc +1 more source
The future of fungal diagnostics: What's next in laboratory testing for invasive fungal infection? [PDF]
Southern-Thomas R +3 more
europepmc +1 more source

