Results 21 to 30 of about 1,114,098 (265)

A long-term in vitro silicon-based microelectrode-neuron connection [PDF]

open access: yes, 1988
A novel method for long-term recording and simulation applicable to cultured neurons has been developed. Silicon-based microelectrodes have been fabricated using integrated-circuit technology and micromachining.
Pine, Jerome   +2 more
core   +1 more source

Evaluation of the cell viability of human Wharton's jelly stem cells for use in cell therapy [PDF]

open access: yes, 2012
Human umbilical cord Wharton's jelly stem cells (HWJSCs) are gaining attention as a possible clinical source of mesenchymal stem cells for cell therapy and tissue engineering due to their high accessibility, expansion potential, and plasticity.
Alaminos, Miguel   +9 more
core   +2 more sources

Receptor-mediated targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis [PDF]

open access: yes, 2003
Superparamagnetic iron oxide nanoparticles have been used for many years as magnetic resonance imaging contrast agents or in drug delivery applications.
Berry, C.C.   +3 more
core   +1 more source

Nanoscale integration of single cell biologics discovery processes using optofluidic manipulation and monitoring. [PDF]

open access: yes, 2019
The new and rapid advancement in the complexity of biologics drug discovery has been driven by a deeper understanding of biological systems combined with innovative new therapeutic modalities, paving the way to breakthrough therapies for previously ...
Chen, Ching   +17 more
core   +1 more source

Optimization of insect cell based protein production processes - online monitoring, expression systems, scale-up [PDF]

open access: yes, 2013
Due to the increasing use of insect cell based expression systems in research and industrial recombinant protein production, the development of efficient and reproducible production processes remains a challenging task.
A Axen   +115 more
core   +1 more source

Surface modification of a polyether-urethane with RGD-containing peptides for enhanced cell attachment and signalling [PDF]

open access: yes, 2005
of article examining the chemical modification of polyurethane with RGD-containing peptides offers a means of encouraging the adhesion, spreading and proliferation of cells cultured on its surface.
Black, R.A.   +4 more
core  

Canonical Wnt signals combined with suppressed TGFβ/BMP pathways promote renewal of the native human colonic epithelium [PDF]

open access: yes, 2013
Background: A defining characteristic of the human intestinal epithelium is that it is the most rapidly renewing tissue in the body. However, the processes underlying tissue renewal and the mechanisms that govern their coordination have proved difficult ...
Ahmed El Hadi   +63 more
core   +1 more source

Study on human chondrocyte culture viability for autologous transplantation in clinical application [PDF]

open access: yes, 2003
Objective: The limited regenerative capacity of the cartilage tissuemakes the treatment of chondral lesions difficult. The techniquescurrently available to treat cartilage lesions may relieve symptoms,but do not regenerate the injured tissue.
Christiane Lombello   +2 more
core  

Fabrication of multi-well chips for spheroid cultures and implantable constructs through rapid prototyping techniques [PDF]

open access: yes, 2015
Three-dimensional (3D) culture models are widely used in basic and translational research. In this study, to generate and culture multiple 3D cell spheroids, we exploited laser ablation and replica molding for the fabrication of polydimethylsiloxane ...
Abbott   +72 more
core   +2 more sources

Overexpression of Large-Conductance Calcium-Activated Potassium Channels in Human Glioblastoma Stem-Like Cells and Their Role in Cell Migration [PDF]

open access: yes, 2017
Glioblastomas (GBMs) are brain tumors characterized by diffuse invasion of cancer cells into the healthy brain parenchyma, and establishment of secondary foci. GBM cells abundantly express large-conductance, calcium-activated potassium (BK) channels that
Abdullaev   +49 more
core   +1 more source

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