Results 21 to 30 of about 2,740,660 (385)
Pharmaceuticals, 2022 Despite tremendous advancements in technologies and resources, drug discovery still remains a tedious and expensive process. Though most cells are cultured using 2D monolayer cultures, due to lack of specificity, biochemical incompatibility, and cell-to ...
S. M. Badr-Eldin +4 more
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Processes, 2020 Bioreactors have proven useful for a vast amount of applications. Besides classical large-scale bioreactors and fermenters for prokaryotic and eukaryotic organisms, micro-bioreactors, as specialized bioreactor systems, have become an invaluable tool for ...
C. Grün, B. Altmann, E. Gottwald
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Implications of Three-Dimensional Cell Culture in Cancer Therapeutic Research
Frontiers in Oncology, 2022 Replicating the naturalistic biomechanical milieu of cells is a primary requisite to uncover the fundamental life processes. The native milieu is significantly not replicated in the two-dimensional (2D) cell cultures.
Kolluri Poornima +11 more
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Razor scrape assay, an alternative variation to wound and healing assays
MethodsX, 2020 Cell migration is the process by which cells move through tissues, and it is crucial to carry out a wide variety of physiological and pathological processes.
Jesús Antonio Lara-Reyes +8 more
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Cells, 2022 Inadequacy of most animal models for drug efficacy assessments has led to the development of improved in vitro models capable of mimicking in vivo exposure scenarios.
Hadi Hashemzadeh +5 more
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3D Cell Culture—Can It Be As Popular as 2D Cell Culture?
Advanced NanoBiomed Research, 2021 A 2D cell culture, a technology used for a long time in the field of life sciences, refers to the growth of cells on a flat surface. The application of this technology enables humans to study the physiological and pathological activities of cells in ...
Miao Sun +7 more
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Frontiers in Molecular Biosciences, 2021 Skeletal reconstruction is necessary in cases of bone defects created by tumors, trauma, and abnormalities. Regeneration of bone defects remains a critical problem, and current approaches are based on biocompatible scaffolds. Spheroids represent a simple
Iñigo Gaitán-Salvatella +4 more
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An introductory undergraduate course covering animal cell culture techniques [PDF]
Biochemistry and Molecular Biology Education, 2004 Paul Mozdziak +2 more
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Recent Advances in Three-Dimensional Stem Cell Culture Systems and Applications
Stem Cells International, 2021 Cell culture is one of the most core and fundamental techniques employed in the fields of biology and medicine. At present, although the two-dimensional cell culture method is commonly used in vitro, it is quite different from the cell growth ...
Xiaowen Wu +4 more
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The contribution of age structure to cell population responses to targeted therapeutics [PDF]
, 2012 Cells grown in culture act as a model system for analyzing the effects of anticancer compounds, which may affect cell behavior in a cell cycle position-dependent manner.
Ackleh +52 more
core +7 more sources