Results 21 to 30 of about 2,687,568 (379)

Translating the combination of gene therapy and tissue engineering for treating recessive dystrophic epidermolysis bullosa [PDF]

open access: yesEuropean Cells & Materials, 2018
The combination of gene therapy and tissue engineering is one of the most promising strategies for the treatment of recessive dystrophic epidermolysis bullosa (RDEB).
A Dakiw Piaceski   +8 more
doaj   +1 more source

Trends in the global organoid technology and industry: from organogenesis in a dish to the commercialization of organoids [PDF]

open access: yesOrganoid, 2021
Animal models have been standard methods for non-clinical research in drug development for decades. However, many drugs that have shown satisfactory results in non-clinical studies have failed in the clinical stage, presumably because animal data are not
Hanbyeol Lee   +3 more
doaj   +1 more source

Explant Culture of Ovarian Tissue

open access: yesVan Tıp Dergisi, 2022
INTRODUCTION: In this study, it was aimed to isolate, reproduce and characterize stromal cells migrating from tissues by creating ovarian tissue explant culture.
Murat Serkant Ünal   +6 more
doaj   +1 more source

Implications of Three-Dimensional Cell Culture in Cancer Therapeutic Research

open access: yesFrontiers in Oncology, 2022
Replicating the naturalistic biomechanical milieu of cells is a primary requisite to uncover the fundamental life processes. The native milieu is significantly not replicated in the two-dimensional (2D) cell cultures.
Kolluri Poornima   +11 more
semanticscholar   +1 more source

Advanced 3D Cell Culture Techniques in Micro-Bioreactors, Part II: Systems and Applications

open access: yesProcesses, 2020
In this second part of our systematic review on the research area of 3D cell culture in micro-bioreactors we give a detailed description of the published work with regard to the existing micro-bioreactor types and their applications, and highlight ...
B. Altmann   +3 more
semanticscholar   +1 more source

Impact of experiential learning among medical undergraduates: A randomized controlled trial

open access: yesJournal of Education and Health Promotion, 2020
BACKGROUND: Experiential learning sessions as a teaching aid have been applied early in the medical undergraduate curriculum to improve the knowledge and inculcate research interest.
Akila Prashant   +3 more
doaj   +1 more source

Advanced 3D Cell Culture Techniques in Micro-Bioreactors, Part I: A Systematic Analysis of the Literature Published between 2000 and 2020

open access: yesProcesses, 2020
Bioreactors have proven useful for a vast amount of applications. Besides classical large-scale bioreactors and fermenters for prokaryotic and eukaryotic organisms, micro-bioreactors, as specialized bioreactor systems, have become an invaluable tool for ...
C. Grün, B. Altmann, E. Gottwald
semanticscholar   +1 more source

Razor scrape assay, an alternative variation to wound and healing assays

open access: yesMethodsX, 2020
Cell migration is the process by which cells move through tissues, and it is crucial to carry out a wide variety of physiological and pathological processes.
Jesús Antonio Lara-Reyes   +8 more
doaj   +1 more source

Fingerprinting Metabolic Activity and Tissue Integrity of 3D Lung Cancer Spheroids under Gold Nanowire Treatment

open access: yesCells, 2022
Inadequacy of most animal models for drug efficacy assessments has led to the development of improved in vitro models capable of mimicking in vivo exposure scenarios.
Hadi Hashemzadeh   +5 more
doaj   +1 more source

3D Cell Culture—Can It Be As Popular as 2D Cell Culture?

open access: yesAdvanced NanoBiomed Research, 2021
A 2D cell culture, a technology used for a long time in the field of life sciences, refers to the growth of cells on a flat surface. The application of this technology enables humans to study the physiological and pathological activities of cells in ...
Miao Sun   +7 more
semanticscholar   +1 more source

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