Experimental liver models: From cell culture techniques to microfluidic organs‐on‐chip
Liver international (Print), 2021 The liver is one of the most studied organs of the human body owing to its central role in xenobiotic and drug metabolism. In recent decades, extensive research has aimed at developing in vitro liver models able to mimic liver functions to study ...
Michela Anna Polidoro +4 more
semanticscholar +1 more source
Trends in the global organoid technology and industry: from organogenesis in a dish to the commercialization of organoids [PDF]
Organoid, 2021 Animal models have been standard methods for non-clinical research in drug development for decades. However, many drugs that have shown satisfactory results in non-clinical studies have failed in the clinical stage, presumably because animal data are not
Hanbyeol Lee +3 more
doaj +1 more source
Development and validation of a vero cell-based suspension method for the detection of Zika virus
Revista Peruana de Medicina Experimental y Salud Pública, 2023 Objective. To develop and validate a cell suspension method using Vero 76 cells for culturing Zika virus (ZIKV) based on infection of detached freshly seeded cells. Material and methods.
Dina Popuche +5 more
doaj +1 more source
Explant Culture of Ovarian Tissue
Van Tıp Dergisi, 2022 INTRODUCTION: In this study, it was aimed to isolate, reproduce and characterize stromal cells migrating from tissues by creating ovarian tissue explant culture.
Murat Serkant Ünal +6 more
doaj +1 more source
Advanced 3D cell culture techniques in micro-bioreactors, Part II: Systems and applications [PDF]
, 2021 In this second part of our systematic review on the research area of 3D cell culture in micro-bioreactors we give a detailed description of the published work with regard to the existing micro-bioreactor types and their applications, and highlight ...
Altmann, B. +3 more
core +2 more sources
Translating the combination of gene therapy and tissue engineering for treating recessive dystrophic epidermolysis bullosa [PDF]
European Cells & Materials, 2018 The combination of gene therapy and tissue engineering is one of the most promising strategies for the treatment of recessive dystrophic epidermolysis bullosa (RDEB).
A Dakiw Piaceski +8 more
doaj +1 more source
Processes, 2020 Bioreactors have proven useful for a vast amount of applications. Besides classical large-scale bioreactors and fermenters for prokaryotic and eukaryotic organisms, micro-bioreactors, as specialized bioreactor systems, have become an invaluable tool for ...
C. Grün, B. Altmann, E. Gottwald
semanticscholar +1 more source
Advanced 3D Cell Culture Techniques in Micro-Bioreactors, Part II: Systems and Applications
Processes, 2020 In this second part of our systematic review on the research area of 3D cell culture in micro-bioreactors we give a detailed description of the published work with regard to the existing micro-bioreactor types and their applications, and highlight ...
B. Altmann +3 more
semanticscholar +1 more source
Impact of experiential learning among medical undergraduates: A randomized controlled trial
Journal of Education and Health Promotion, 2020 BACKGROUND: Experiential learning sessions as a teaching aid have been applied early in the medical undergraduate curriculum to improve the knowledge and inculcate research interest.
Akila Prashant +3 more
doaj +1 more source
Recent Advances in Three-Dimensional Stem Cell Culture Systems and Applications
Stem Cells International, 2021 Cell culture is one of the most core and fundamental techniques employed in the fields of biology and medicine. At present, although the two-dimensional cell culture method is commonly used in vitro, it is quite different from the cell growth ...
Xiaowen Wu +4 more
semanticscholar +1 more source