Results 41 to 50 of about 579,141 (263)

A cell line derived from BBN (N-butyl-N-[4-hydroxybutyl]-nitrosamine)-induced rat bladder cancer: establishment and scanning electron microscopic cell surface characteristics

open access: yes, 1978
This research was performed to establish a cell line from experimental bladder tumor and to discuss the biological characteristics of the cell line so established. Tissue cultures of epithelial cells were derived from a rat bladder cancer induced by BBN.
Nishi, Mitsuo
core   +1 more source

Integrated multi-assay culture model for stem cell chondrogenic differentiation [PDF]

open access: yes, 2019
Recent osteochondral repair strategies highlight the promise of mesenchymal progenitors, an accessible stem cell source with osteogenic and chondrogenic potential, used in conjunction with biomaterials for tissue engineering.
Scotchford, Colin   +9 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Towards Commercial Production of Sponge Medicines

open access: yes, 2009
Sponges can provide potential drugs against many major world-wide occurring diseases. Despite the high potential of sponge derived drugs no sustainable production method has been developed.
Marieke Koopmans   +6 more
core   +1 more source

Lab-in-a-trench platform for real-time monitoring of cell surface protein expression [PDF]

open access: yes, 2010
In this work we for the first time demonstrate real-time monitoring of the expression of membrane proteins in native, live cells, free of hydrodynamic stress at single cell resolution. This micro-optofluidic mechanism is uniquely enabled by the intricate
Dimov, Ivan Krastev   +6 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

3D cell culture models of epithelial tissues [PDF]

open access: yes, 2019
Cells in tissues in vivo face a very different microenvironment than typical cultured cells plated on a plastic dish. Already several decades ago, cell biologists observed that cell lines show dramatically different morphology and growth characteristics ...
Zhang, K. (Kai)   +5 more
core   +1 more source

Current Approaches to Three-Dimensional Cell Culture System [PDF]

open access: yes, 2020
İki boyutlu (2B) hücre kültürü, hücre temelli araştırmalar için değerli bir yöntemdir ancak in vivo yanıtlar hakkında öngörülemeyen, yanıltıcı veriler sağlayabilir. Son yirmi yılda, hücresel mikro çevrenin (örneğin hücre dışı matris ve interstisyel sıvı)
Polat Hopcan, Elif, Elif POLAT
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

3D Cardiac Cell Culture: A Critical Review of Current Technologies and Applications [PDF]

open access: yes, 2019
Three-dimensional (3D) cell culture is often mentioned in the context of regenerative medicine, for example, for the replacement of ischemic myocardium with tissue-engineered muscle constructs.
Zuppinger, Christian
core   +1 more source

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