Results 21 to 30 of about 583,264 (306)

Evaluation of apoptotic effect of crocin, cisplatin, and their combination in human oral squamous cell carcinoma cell line HN5

open access: yesDental Research Journal, 2021
Background: Squamous cell carcinoma (SCC) is the most common oral malignancy with high rate of mortality. Cisplatin, as the most effective chemotherapy drug, has side effects.
Fatima Bijani   +5 more
doaj   +1 more source

Fingerprinting Metabolic Activity and Tissue Integrity of 3D Lung Cancer Spheroids under Gold Nanowire Treatment

open access: yesCells, 2022
Inadequacy of most animal models for drug efficacy assessments has led to the development of improved in vitro models capable of mimicking in vivo exposure scenarios.
Hadi Hashemzadeh   +5 more
doaj   +1 more source

Preparation and use of serum-free aggregating brain cell cultures for routine neurotoxicity screening [PDF]

open access: yes, 2011
The nervous system is a frequent target of industrial chemicals, pharmaceuticals, and environmental pollutants. To screen large numbers of compounds for their neurotoxic potential, in vitro systems are required which combine organ-specific traits with ...
Honegger, P., Zurich. M.-G.,
core   +1 more source

Diosgenin production in Trigonella foenum-graecum (Fenugreek) cell cultures in response to yeast extract elicitation [PDF]

open access: yes, 2021
© 2021, The Author(s), under exclusive licence to Springer Nature B.V. part of Springer Nature.Diosgenin is an important precursor of steroidal drugs and a number of biotechnology techniques, including gene transfer and elicitation studies, are used to ...
ÖZDEN, Sibel   +3 more
core   +1 more source

Optimized Primary Culture and Subculture of Granulosa Cells

open access: yesPharmaceutical and Biomedical Research, 2022
Background: Primordial follicle includes an oocyte surrounded by a layer of somatic cells called Granulosa Cells (GCs). GCs, also known as nurse cells, are an important protective element for the growth and survival of oocytes.
Nadia Fallah   +4 more
doaj  

Biotechnology apprenticeship for secondary-level students: teaching advanced cell culture techniques for research [PDF]

open access: yes, 2002
The purpose of this article is to discuss small-group apprenticeships (SGAs) as a method to in-struct cell culture techniques to high school participants.
Sumant Kulcarni   +7 more
core   +1 more source

An Modified Primary Culture Method of Breast Cancer-associated Fibroblasts

open access: yesZhongliu Fangzhi Yanjiu, 2018
Objective To establish a rapid and high efficient method of primary culture of BCAFs by improving primary culture methods of common breast cancer-associated fibroblasts (BCAFs).
LI Zhiyong, BAI Xue, CAI Huiyun
doaj   +1 more source

Memantine protects the cultured rat hippocampal neurons treated by NMDA and amyloid β1–42

open access: yesFrontiers in Neuroscience, 2023
Alzheimer’s disease (AD) is a devastating neurodegenerative condition with no effective treatments. Recent research highlights the role of NMDA receptors in AD development, as excessive activation of these receptors triggers excitotoxicity. Memantine, an
Nataliia M. Rozumna   +2 more
doaj   +1 more source

The changing role of cell culture in the generation of transgenic livestock [PDF]

open access: yes, 1999
Transgenesis may allow the generation of farm animals with altered phenotype, animal models for research and animal bioreactors. Although such animals have been produced, the time and expense involved in generating transgenic livestock and then ...
Whitelaw, C B, Farini, E, Webster, J
core   +1 more source

Evaluation of a composite skin substitute to treat venous stasis ulcers: a pilot study

open access: yesBrazilian Journal of Transplantation, 2006
Introduction: Venous leg ulcers represent a therapeutic challenge, and they are associated to significant morbidity and cost. Many advances have been made to develop and apply biological skin substitutes, showing they can be beneficial for patients with
Paula Dadalti-Granja   +7 more
doaj   +1 more source

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