Memantine protects the cultured rat hippocampal neurons treated by NMDA and amyloid β1–42
Frontiers in Neuroscience, 2023 Alzheimer’s disease (AD) is a devastating neurodegenerative condition with no effective treatments. Recent research highlights the role of NMDA receptors in AD development, as excessive activation of these receptors triggers excitotoxicity. Memantine, an
Nataliia M. Rozumna +2 more
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Nanoscale integration of single cell biologics discovery processes using optofluidic manipulation and monitoring. [PDF]
, 2019 The new and rapid advancement in the complexity of biologics drug discovery has been driven by a deeper understanding of biological systems combined with innovative new therapeutic modalities, paving the way to breakthrough therapies for previously ...
Chen, Ching +17 more
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Evaluation of a composite skin substitute to treat venous stasis ulcers: a pilot study
Brazilian Journal of Transplantation, 2006 Introduction: Venous leg ulcers represent a therapeutic challenge, and they are associated to significant morbidity and cost. Many advances have been made to develop and apply biological skin substitutes, showing they can be beneficial for patients with
Paula Dadalti-Granja +7 more
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Nuclear DNA and protein content evaluation in Taxus plant cell cultures using multiparameter flow cytometry [PDF]
, 2009 Plant cell cultures of Taxus provide the most reliable production methods for the anti-cancer drug paclitaxel. In order to comprehend the inherent culture heterogeneity and production variability in cell cultures, it is essential that the cellular ...
Amit Shavit +2 more
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Current Approaches to Three-Dimensional Cell Culture System
Namık Kemal Tıp Dergisi, 2020 Two-dimensional (2D) cell culture is a valuable method for cell-based research, However, it may provide unpredictable, misleading data on in vivo responses.
Elif POLAT
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Environmental monitoring of Mycobacterium bovis in badger feces and badger sett soil by real-time PCR, as confirmed by immunofluorescence, immunocapture, and cultivation [PDF]
, 1999 Real-time PCR was used to detect and quantify Mycobacterium bovis cells in naturally infected soil and badger faeces. Immunomagnetic capture, immunofluorescence and selective culture confirmed species identification and cell viability.
Sweeney, F. P. +6 more
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Modeling Central Nervous System Injury In Vitro: Current Status and Promising Future Strategies
Biomedicines, 2022 The central nervous system (CNS) injury, which occurs because of mechanical trauma or ischemia/hypoxia, is one of the main causes of mortality and morbidity in the modern society.
Kristina Pilipović +3 more
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Journal of Applied Oral Science, 2007 The objective of the present study was to characterize bone cells grown in two culture media, and to determine the effective concentration of OP-1 on the growth of osteo-1 cells.
Adriane Yaeko Togashi +4 more
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Long-Term Culture of Rat Hippocampal Neurons at Low Density in Serum-Free Medium: Combination of the Sandwich Culture Technique with the Three-Dimensional Nanofibrous Hydrogel PuraMatrix [PDF]
, 2014 The primary culture of neuronal cells plays an important role in neuroscience. There has long been a need for methods enabling the long-term culture of primary neurons at low density, in defined serum-free medium. However, the lower the cell density, the
Kaneko Ai +3 more
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In vitro cytotoxicity assessment of the 3D printed polymer based epoxy resin intended for use in dentistry [PDF]
Vojnosanitetski Pregled, 2019 Background/Aim. There is limited published evidence on the cytotoxicity of 3D printed polymer materials for dentistry applications, despite that they are now being widely used in medicine.
Puškar Tatjana +6 more
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