Results 141 to 150 of about 16,449,484 (363)
Cell cycle-coupled transcriptional network orchestrates human B cell fate bifurcation [PDF]
Nicholas A. Pease, Jing‐Yu Fan, Swapnil Keshari, Jo Anne Stratton, Peter Gerges, Betsy Ann Varghese, Narayanan Nampoothiri VP, Christopher S. McGinnis, Wenxi Zhang, Steven B Gierlack, T. Raja Swaminathan, Ashish Sachan, Godhev Manakkat Vijay, Lídia Hernandez, Zarifeh Heidari Rarani, Camila Macedo, Diana Metes, Ansuman T. Satpathy, Abhinav K. Jain, Nidhi Sahni, Wayne Stallaert, Jishnu Das, Harinder Singh +22 moreopenalex +1 more sourceSupplementary Figure 3 from SOX10 Ablation Arrests Cell Cycle, Induces Senescence, and Suppresses Melanomagenesis
, 2023 Julia C. Cronin, Dawn E. Watkins‐Chow, Art Incao, Joanne H. Hasskamp, Nicola Schönewolf, Lauren G. Aoude, Nicholas K. Hayward, Boris C. Bastian, Reinhard Dummer, Stacie K. Loftus, William J. Pavan +10 moreopenalex +1 more sourceReduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh +8 morewiley +1 more sourceSupplementary data, tables and figures from Altered Cell-Cycle Control, Inflammation, and Adhesion in High-Risk Persistent Bronchial Dysplasia
, 2023 Daniel T. Merrick, Michael G. Edwards, Wilbur A. Franklin, Michio Sugita, Robert L. Keith, York E. Miller, Micah Friedman, Lori D. Dwyer‐Nield, Meredith A. Tennis, Mary C. O’Keefe, Elizabeth J. Donald, Jessica M. Malloy, Adrie van Bokhoven, Storey Wilson, Peter J. Koch, Charlene O’Shea, Christopher D. Coldren, David J. Orlicky, Xian Lu, Anna E. Barón, Greg Hickey, Timothy C. Kennedy, Roger Powell, Lynn E. Heasley, Paul A. Bunn, Mark W. Geraci, Raphael A. Nemenoff +26 moreopenalex +1 more sourceImproving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann +15 morewiley +1 more sourceCytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock +10 morewiley +1 more sourceSupplementary Figure 1 from Dual CDK4/CDK6 Inhibition Induces Cell-Cycle Arrest and Senescence in Neuroblastoma
, 2023 JulieAnn Rader, Mike R. Russell, Lori S. Hart, Michael S. Nakazawa, Lili T. Belcastro, Daniel Martı́nez, Yimei Li, Erica L. Carpenter, Edward F. Attiyeh, Sharon J. Diskin, Sunkyu Kim, Sudha Parasuraman, Giordano Caponigro, Robert W. Schnepp, Andrew Wood, Bruce Pawel, Kristina A. Cole, John M. Maris +17 moreopenalex +1 more source
