Results 161 to 170 of about 16,339,920 (405)

Study of radiation effects on mammalian cells in vitro [PDF]

, 1968
Radiation effect on single cells and cell populations of Chinese hamster lung tissue is studied in vitro. The rate and position as the cell progresses through the generation cycle shows division delay, changes in some biochemical processes in the cell ...
Sinclair, W. K.
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Single-cell transcriptomes reveal the mechanism for a breast cancer prognostic gene panel. [PDF]

, 2018
The clinical benefits of the MammaPrint® signature for breast cancer is well documented; however, how these genes are related to cell cycle perturbation have not been well determined.
Cai, Jin, Chen, Xuelian, Kabeer, Mustafa H, Li, Shengwen Calvin, Loudon, William G, Nangia, Chaitali S, Plant, Ashley S, Stucky, Andres, Torno, Lilibeth, Zhang, Gang, Zhong, Jiang F   +10 more
core  

Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization.

Molecular Biology of the Cell, 1998
P. Spellman, G. Sherlock, Michael Ruogu Zhang, V. Iyer, Klaus E. Anders, M. Eisen, P. Brown, D. Botstein, B. Futcher   +8 more
semanticscholar   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Maspin/SerpinB5 is a cytoskeleton-binding protein that regulates epithelial cell shape

Communications Biology
Maspin/SerpinB5 is an abundant and pleiotropic protein mostly expressed by epithelia. Initially described as a tumor suppressor, it has been reported as a regulator of cell adhesion, migration, and invasion.
Luiz E. da Silva, Lia M. G. Paim, Tatiana Lyalina, Ana P. J. Menezes, Julia P. C. da Cunha, Susanne Bechstedt, Nathalie Cella   +6 more
doaj   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

Molecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo, Carlos M. Martínez‐Cáceres, Manuel Bernabé‐García, Vicente Munitiz, David Ruiz de Angulo, Pascual Parrilla, Ángeles Ortiz, Luisa F. Martínez de Haro, María L. Cayuela   +8 more
wiley   +1 more source

Sumo-regulatory SENP2 controls the homeostatic squamous mitosis-differentiation checkpoint

Cell Death and Disease
Squamous or epidermoid cancer arises in stratified epithelia but also is frequent in the non-epidermoid epithelium of the lung by unclear mechanisms.
Jesús Galán-Vidal, Lorena García-Gaipo, Rut Molinuevo, Samantha Dias, Alex Tsoi, Javier Gómez-Román, James T. Elder, Helfrid Hochegger, Alberto Gandarillas   +8 more
doaj   +1 more source

Cycle life test and failure model of nickel-hydrogen cells [PDF]

Six ampere hour individual pressure vessel nickel hydrogen cells were charge/discharge cycled to failure. Failure as used here is defined to occur when the end of discharge voltage degraded to 0.9 volts.
Smithrick, J. J.
core   +1 more source

The Mitotic Cycle time of Root Meristem Cells ofHelianthus Annuus [PDF]

, 1969
Jordanka Georgieva Todorova, Vittoria Nuti Ronchi   +1 more
openalex   +1 more source