Results 181 to 190 of about 16,449,484 (363)

Cell cycle dynamics and window of MUTE action during the terminal division of stomata and ramification of its loss-of-function on the cell cycle of an uncommitted precursor

, 2022
Daniel T. Zuch, Arvid Herrmann, Eundeok Kim, Keiko U. Torii   +3 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Probabilistic modeling of cell cycle dynamics in response to cell cycle targeting chemotherapy drugs to guide treatment strategies. [PDF]

PLoS Comput Biol
Ma C, Gurkan-Cavusoglu E.
europepmc   +1 more source

Effect of long non-coding RNA DUXAP8 on proliferation, cycle and apoptosis of ovarian cancer cells by regulating miR-4677-3p

, 2021
CHEN Cen, Dan Su, LI Ningwei, Qin Jiang, WANG Yazhou   +4 more
openalex   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Targeting cell cycle in leukemia: "Is palbociclib the game-changer?": A review. [PDF]

Medicine (Baltimore)
Azizan MA, Abeden Z, Shamsuddin NHN, Ahid F, Mohd Yusoff N, Ismail MN, Ng SK, Isa A.   +7 more
europepmc   +1 more source

Movie 3 from Mesenchymal Stem Cell–Derived Exosomes Stimulate Cycling Quiescence and Early Breast Cancer Dormancy in Bone Marrow

, 2023
Sarah A. Bliss, Garima Sinha, Oleta A. Sandiford, Lisa Williams, Daniel J. Engelberth, Khadidiatou Guiro, Leidy Isenalumhe, Steven J. Greco, Seda Ayer, Margarette Bryan, Rakesh Kumar, Nicholas M. Ponzio, Pranela Rameshwar   +12 more
openalex   +1 more source

The cell cycle in stem cell proliferation, pluripotency and differentiation

Nature Cell Biology, 2019
Lijun Liu, W. Michowski, Aleksandra A. Kolodziejczyk, P. Sicinski   +3 more
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Conditional Localization Pharmacology Manipulates the Cell Cycle with Spatiotemporal Precision. [PDF]

J Am Chem Soc
Deng C, Lan YC, Chen GY, Ekeabu CS, Doan Q, Chung M, Lampson MA, Chenoweth DM.   +7 more
europepmc   +1 more source