Results 211 to 220 of about 1,815,617 (316)

FuChi: A cell cycle biosensor for investigating cell-cycle kinetics during avian development

Sudderick ZR, Briggs T, Mubarak S, Van Kerckvoorde M, Hernandez-Rodriguez AR, Panda SK, Riddell J, Batho-Samblas C, Taylor L, McTeir L, Meunier D, Findlay A, Roberts F, Raper A, Sakaue-Sawano A, Miyawaki A, Rainger J, Schoenebeck JJ, Weijer CJ, McGrew MJ, Headon DJ, Davey MG, Mort RL, Glover JD.   +23 more
europepmc   +1 more source

CDH1 Orchestrates Anabolic Events to Promote Cell Cycle Initiation. [PDF]

Adv Sci (Weinh)
Mao YZ, Zhang JJ, You MQ, Wang H, Lin Y, Fang Y, Zhang HL, Qu YY, Zhou Q, Wang M, Li G, Guo ZF, Xu M, Liu J, Lin PC, Yuan YY, Kang Y, Zhao SM, Xu W.   +18 more
europepmc   +1 more source

TACC2 Is an Androgen-Responsive Cell Cycle Regulator Promoting Androgen-Mediated and Castration-Resistant Growth of Prostate Cancer

, 2012
Ken‐ichi Takayama, Kuniko Horie‐Inoue, Takashi Suzuki, Tomohiko Urano, Kazuhiro Ikeda, Tetsuya Fujimura, Satoru Takahashi, Yukio Homma, Yasuyoshi Ouchi, Satoshi Inoue   +9 more
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

High-content phenotyping reveals Golgi dynamics and their role in cell cycle regulation. [PDF]

J Cell Biol
Cao X, Peng Y, Yang M, Gan M, Zhang D, Zhou S, Takao D.   +6 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Cell cycle regulator MYBL2 is a distinct vulnerability in acute myeloid leukemia. [PDF]

Cell Death Discov
Küchler S, Brilloff S, Schäfer S, Rahimian E, Kufrin V, Peri SS, Musa J, Grünewald TGP, Schewe DM, Ball CR, Bornhäuser M, Glimm H, Bill M, Wurm AA.   +13 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Deciphering the Role of DNA Polymerase Eta on the Incorporation and Bypass of Inosine and Cell Cycle Arrest. [PDF]

Int J Mol Sci
Lin JC, Averill JR, Jung H.
europepmc   +1 more source