Results 211 to 220 of about 16,449,484 (363)

TEAD-independent mechanisms of YAP function in cardiomyocyte cell cycle reentry. [PDF]

Life Sci Alliance
Xie B, Steimle J, Deshmukh V, Liu L, Tsai CR, Heallen TR, Paltzer W, Morikawa Y, Meng F, Wang J, Martin JF.   +10 more
europepmc   +1 more source

Inhibition of S-adenosylhomocysteine hydrolase decreases cell mobility and cell proliferation through cell cycle arrest.

, 2015
Sae Jeong Park, Hyun Kyung Kong, Ye Sol Kim, Yeon Seon Lee, Jong Hoon Park   +4 more
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A vertically integrated system for tracking and assessing cell-cycle-aware phenotypes under confinement. [PDF]

APL Bioeng
Pezzotti M, Torchia E, Zimmermann J, Rigolli S, Enrico A, Sarchi M, Sante MD, Pasqualini FS.   +7 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Esomeprazole inhibits proliferation of scleroderma fibroblasts via cell cycle regulation. [PDF]

Front Pharmacol
Khan MA, Koniyan S, Ahir M, Jegga AG, Mayes MD, Gius D, Leung J, Bonnen MD, Montesi SB, Ghebre YT.   +9 more
europepmc   +1 more source

Transcriptional Profiling of the Cell Cycle Checkpoint Gene Krüppel-Like Factor 4 Reveals a Global Inhibitory Function in Macromolecular Biosynthesis

, 2006
Erika M. Whitney, Amr M. Ghaleb, Xinming Chen, AND VINCENT W. YANG   +3 more
openalex   +1 more source

Visualizing spatiotemporal dynamics of multicellular cell-cycle progression.

Cell, 2008
A. Sakaue-Sawano, H. Kurokawa, T. Morimura, A. Hanyu, H. Hama, Hatsuki Osawa, S. Kashiwagi, K. Fukami, T. Miyata, H. Miyoshi, T. Imamura, M. Ogawa, H. Masai, A. Miyawaki   +13 more
semanticscholar   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Cell cycle, cell division, cell death

Molecular Biology of the Cell, 2019
Maddox, Amy Shaub, Skotheim, Jan M.
openaire   +2 more sources