Results 211 to 220 of about 1,827,380 (267)

Focal Adhesion and Cancer Cell Cycle-Associated Resistance. [PDF]

ACS Omega
Ruksha TG, Palkina NV, Lapkina EZ, Liu K.   +3 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Big1 is a cell-cycle regulator linking cell size to basal body number in Tetrahymena thermophila. [PDF]

Curr Biol
Stemm-Wolf AJ, Soh AWJ, Mitchell LE, Sun H, Collet E, Dholakia GL, Raju V, Hesselberth JR, Taliaferro JM, Murphy RF, Heasley LR, Pearson CG.   +11 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Arecoline as a Novel Scaffold Targeting the ATAD2 Bromodomain for Cell Cycle Modulation. [PDF]

Pharmaceutics
Lin TS, Wan J, He J, Cui S, Huang Y, Zhang B, Huang HY, Zhu K, Chen J, Zhang T, Li S, Hu L, Wang Y, Huang HD, Tang P, Lin YC.   +15 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Peculiarities of the Mammalian Oocyte Cell Cycle. [PDF]

Physiology (Bethesda)
Wetherall B, Madgwick S.
europepmc   +1 more source

Correction: Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway

Molecular Cancer
Joshua E Allen, Gabriel Krigsfeld, Luv Patel, Patrick A Mayes, David T Dicker, Gen Sheng Wu, Wafik S El-Deiry   +6 more
doaj   +1 more source

Chemical genetics reveals Leishmania KKT2 and CRK9 kinase activity is required for cell cycle progression. [PDF]

PLoS Pathog
Carnielli JBT, Brannigan JA, Ramos PZ, Jones NG, Couñago RM, Sjö P, Lima APCA, Wilkinson AJ, Mottram JC.   +8 more
europepmc   +1 more source

Association Between CDH1 Downregulation and Lymphocyte Cell-Cycle Dysfunction in Alzheimer's Disease and Mild Cognitive Impairment. [PDF]

Cell Mol Neurobiol
Monllor P, Lopez B, Lloret MA, Leon JL, Lopez E, Badia MC, Lloret A.   +6 more
europepmc   +1 more source