Results 281 to 290 of about 16,449,484 (363)

CDH1 Orchestrates Anabolic Events to Promote Cell Cycle Initiation. [PDF]

Adv Sci (Weinh)
Mao YZ, Zhang JJ, You MQ, Wang H, Lin Y, Fang Y, Zhang HL, Qu YY, Zhou Q, Wang M, Li G, Guo ZF, Xu M, Liu J, Lin PC, Yuan YY, Kang Y, Zhao SM, Xu W.   +18 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Pharmacological inhibition of frizzled 4 delays cell cycle progression and limits oral squamous cell carcinoma growth. [PDF]

Front Cell Dev Biol
Destefani R, Valookkaran IJ, Bensland S, Meisel CT, Porcheri C.   +4 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

A concise guide to fluorescent cell cycle reporters for live-cell imaging. [PDF]

Front Cell Dev Biol
Wang J, Li Y, Luo J, Sharvia S, Chan KY.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Correction: Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway

Molecular Cancer
Joshua E Allen, Gabriel Krigsfeld, Luv Patel, Patrick A Mayes, David T Dicker, Gen Sheng Wu, Wafik S El-Deiry   +6 more
doaj   +1 more source

Tumor cell cycle regulation: integrated perspective of stage characteristics, regulatory networks, and signaling pathway intervention strategies. [PDF]

Mol Biomed
Wan Q, Yang Z, Huang L, Xia Y, Long L, Xu Z, Li J.   +6 more
europepmc   +1 more source

The mechanism of cell-cycle-dependent proteasomal degradation of archaeal ESCRT-III homolog CdvB in Sulfolobus. [PDF]

EMBO J
Kuo YW, Traparić J, Foo S, Baum B.
europepmc   +1 more source

AAV Assembled Capsids Are Produced in Cells Blocked From Cell Cycle Progression. [PDF]

Biotechnol Bioeng
Mullick A, Morasse A, Leclerc M, Liu Z, Liu QY, Leclerc S, Momcilovic M, Viau A, Kamen AA.   +8 more
europepmc   +1 more source