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S Phase of the Cell Cycle [PDF]
Science, 1989 In each cell cycle the complex structure of the chromosome must be replicated accurately. In the last few years there have been major advances in understanding eukaryotic chromosome replication. Patterns of replication origins have been mapped accurately in yeast chromosomes.
Laskey, R. A. +2 more
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Cell Cycle: In and out of the cell cycle
Current Biology, 1994Studies of fission yeast are shedding light on how the same genes allow cells to respond to their environment either by growing and proliferating mitotically or by arresting growth to allow differentiation and meiosis.
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New England Journal of Medicine, 1981
FIFTEEN years ago it seemed that one could selectively damage cancer cells by exploiting simple differences in the cell-cycle kinetics of normal and neoplastic cells.
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FIFTEEN years ago it seemed that one could selectively damage cancer cells by exploiting simple differences in the cell-cycle kinetics of normal and neoplastic cells.
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Cell Cycle: The Life Cycle of a Cell
2013“Where a cell arises, there must be a previous cell”. This early statement of Rudolf Virchow already points to the process that is called cell cycle. It describes a series of events leading to cell division and duplication and can be sectioned into phases that are controlled by a collection of proteins interacting with each other, the cyclines and the ...
Christine Ziegler, Christian Behl
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Centrosomes and The Cell Cycle
Journal of Cell Science, 1989ABSTRACT Centrosomes are the ensemble of organelles that form the poles of the mitotic spindle. We have examined the properties of the mechanisms that control the precise doubling, or reproduction, of centrosomes during the cell cycle. A functional analysis of this event in sea urchin eggs indicates that it is limited by the reproduction
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1997
Viruses depend on the host's machineries to replicate and express their genome. Actively replicating cells have large pools of deoxynucleotides and high levels of key enzyme activities that viruses exploit to their own needs. Some viruses have developed strategies for driving quiescent cells into the S phase of the cell cycle, e.g.
Op De Beeck, Anne +1 more
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Viruses depend on the host's machineries to replicate and express their genome. Actively replicating cells have large pools of deoxynucleotides and high levels of key enzyme activities that viruses exploit to their own needs. Some viruses have developed strategies for driving quiescent cells into the S phase of the cell cycle, e.g.
Op De Beeck, Anne +1 more
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Journal of Cellular Biochemistry, 1998
Cell cycle checkpoint controls play a major role in preventing the development of cancer [see Sherr, 1994, for a more detailed discussion]. Major checkpoints occur at the G1 to S phase transition and at the G2 to M phase transitions. Cancer is a genetic disease that arises from defects in growth-promoting oncogenes and growth-suppressing tumor ...
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Cell cycle checkpoint controls play a major role in preventing the development of cancer [see Sherr, 1994, for a more detailed discussion]. Major checkpoints occur at the G1 to S phase transition and at the G2 to M phase transitions. Cancer is a genetic disease that arises from defects in growth-promoting oncogenes and growth-suppressing tumor ...
openaire +3 more sources