Results 351 to 360 of about 16,339,920 (405)
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Nature reviews. Molecular cell biology, 2021
Helen K. Matthews +2 more
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Helen K. Matthews +2 more
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Journal of Cellular Biochemistry, 1995
AbstractIn this review, we consider apoptosis as a process intimately linked to the cell cycle. There are several reasons for thinking of apoptosis as a cell cycle phenomenon. First, within the organism, apoptosis is almost exclusively found in proliferating tissues.
William Meikrantz, Robert Schlegel
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AbstractIn this review, we consider apoptosis as a process intimately linked to the cell cycle. There are several reasons for thinking of apoptosis as a cell cycle phenomenon. First, within the organism, apoptosis is almost exclusively found in proliferating tissues.
William Meikrantz, Robert Schlegel
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Cell Cycle: Cell-cycle control in a developmental context
Current Biology, 1994Down-regulation of a cyclin specific to the G1 phase of the cell cycle, cyclin E, terminates the initial period of cell proliferation in developing Drosophila embryos.
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Annual Review of Plant Biology, 2003
Cell division in plants is controlled by the activity of cyclin-dependent kinase (CDK) complexes. Although this basic mechanism is conserved with all other eukaryotes, plants show novel features of cell-cycle control in the molecules involved and their regulation, including novel CDKs showing strong transcriptional regulation in mitosis.
James A. H. Murray, Walter Dewitte
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Cell division in plants is controlled by the activity of cyclin-dependent kinase (CDK) complexes. Although this basic mechanism is conserved with all other eukaryotes, plants show novel features of cell-cycle control in the molecules involved and their regulation, including novel CDKs showing strong transcriptional regulation in mitosis.
James A. H. Murray, Walter Dewitte
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Methods in Cell Science, 1999
The yeast Saccharomyces cerevisiae has been an excellent model system for cell cycle studies. Many such studies require cells synchronized in some particular portion of the cell cycle. Here, methods are described for obtaining and examining synchronized cells as they pass through one or more rounds of the cell cycle. The methods are of two types. First,
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The yeast Saccharomyces cerevisiae has been an excellent model system for cell cycle studies. Many such studies require cells synchronized in some particular portion of the cell cycle. Here, methods are described for obtaining and examining synchronized cells as they pass through one or more rounds of the cell cycle. The methods are of two types. First,
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Journal of Theoretical Biology, 1999
The eukaryotic cell division cycle consists of two characteristic states: G1, when replication origins of chromosomes are in a pre-replicative state, and S/G2/M, when they are in a post-replicative state (Nasmyth, 1995). Using straightforward biochemical kinetics, we show that these two states can be created by antagonistic interactions between cyclin ...
Attila Csikász-Nagy +5 more
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The eukaryotic cell division cycle consists of two characteristic states: G1, when replication origins of chromosomes are in a pre-replicative state, and S/G2/M, when they are in a post-replicative state (Nasmyth, 1995). Using straightforward biochemical kinetics, we show that these two states can be created by antagonistic interactions between cyclin ...
Attila Csikász-Nagy +5 more
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2011
Experimental systems to explore life origin: perspectives for understanding primitive mechanisms of cell division. Evolution of bet-hedging mechanisms in cell cycle and embryo development stimulated by weak linkage of stochastic processes. Mechanics of cell shape regulation during the cell cycle. The spindle assembly checkpoint: clock or domino?
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Experimental systems to explore life origin: perspectives for understanding primitive mechanisms of cell division. Evolution of bet-hedging mechanisms in cell cycle and embryo development stimulated by weak linkage of stochastic processes. Mechanics of cell shape regulation during the cell cycle. The spindle assembly checkpoint: clock or domino?
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Cell-cycle checkpoint kinases: checking in on the cell cycle
Current Opinion in Cell Biology, 2000In response to DNA damage, cell-cycle checkpoints integrate cell-cycle control with DNA repair. The idea that checkpoint controls are an integral component of normal cell-cycle progression has arisen as a result of studies in Drosophila and mice.
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2007
Dysregulation of cell cycle signaling is a pathognomonic feature of tumor initiation and progression. An understanding of the key cell cycle components dysregulated in cancer and the molecular mechanisms responsible has led to the generation of new targeted therapeutics.
Richard G. Pestell, Chad D. Knights
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Dysregulation of cell cycle signaling is a pathognomonic feature of tumor initiation and progression. An understanding of the key cell cycle components dysregulated in cancer and the molecular mechanisms responsible has led to the generation of new targeted therapeutics.
Richard G. Pestell, Chad D. Knights
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Cell Cycles in Cell Hierarchies
International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1986In the replacing tissues of the body, namely the bone marrow, testis, and the surface epithelia with their appendages, cell replacement would appear to be achieved using an hierarchically organized proliferative compartment with relatively few ultimate stem cells producing dividing transit cells which eventually differentiate and mature into the ...
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