Results 361 to 370 of about 16,339,920 (405)
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2003
Normal cells possess mechanisms that protect them from the action of oncogenes. Thus, normal primary cells are not affected by neoplastic transformations, whereas the majority of immortal cells used in laboratory cultures have acquired mutations during the immortalization process and are susceptible to being transformed.
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Normal cells possess mechanisms that protect them from the action of oncogenes. Thus, normal primary cells are not affected by neoplastic transformations, whereas the majority of immortal cells used in laboratory cultures have acquired mutations during the immortalization process and are susceptible to being transformed.
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La Clinica terapeutica, 1999
To evaluate the link between cell cycle dysfunctions and tumor formation.A review of the cell cycle mechanism and its regulatory factors which are involved in carcinogenesis.Cell duplication is directed by a precise cellular machine. The engine of this machine is composed of the cyclin-dependent kinases (Cdks).
Pucci B., Giordano A.
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To evaluate the link between cell cycle dysfunctions and tumor formation.A review of the cell cycle mechanism and its regulatory factors which are involved in carcinogenesis.Cell duplication is directed by a precise cellular machine. The engine of this machine is composed of the cyclin-dependent kinases (Cdks).
Pucci B., Giordano A.
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1998
The cell cycle consists of a set of highly ordered events that result in the duplication and division of a cell. This process requires the synthesis of a new copy of DNA, segregation of chromosomes, mitosis, and apportionment of the cellular contents.
Lynda Q. Nguyen, J. Larry Jameson
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The cell cycle consists of a set of highly ordered events that result in the duplication and division of a cell. This process requires the synthesis of a new copy of DNA, segregation of chromosomes, mitosis, and apportionment of the cellular contents.
Lynda Q. Nguyen, J. Larry Jameson
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Cell cycle, CDKs and cancer: a changing paradigm
Nature Reviews. Cancer, 2009Marcos Malumbres, M. Barbacid
semanticscholar +1 more source
2009
Considered here is the cell cycle, which is driven by mitogen growth factors and dampened by cytokine TGFb. Surface integrins help cell proliferation and, of course, c-Myc oncogene. How cell cycle arrest or apoptosis are achieved is to be appreciated. One can consider the proliferation of T lymphocytes, and one will have tumors in mind.
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Considered here is the cell cycle, which is driven by mitogen growth factors and dampened by cytokine TGFb. Surface integrins help cell proliferation and, of course, c-Myc oncogene. How cell cycle arrest or apoptosis are achieved is to be appreciated. One can consider the proliferation of T lymphocytes, and one will have tumors in mind.
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Science, 1996
Uncontrolled cell proliferation is the hallmark of cancer, and tumor cells have typically acquired damage to genes that directly regulate their cell cycles. Genetic alterations affecting p16 INK4a and cyclin D1, proteins that govern phosphorylation of the retinoblastoma protein (RB) and ...
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Uncontrolled cell proliferation is the hallmark of cancer, and tumor cells have typically acquired damage to genes that directly regulate their cell cycles. Genetic alterations affecting p16 INK4a and cyclin D1, proteins that govern phosphorylation of the retinoblastoma protein (RB) and ...
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Seminars in Cell and Developmental Biology, 2020
Diego MartÃnez-Alonso, Marcos Malumbres
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Diego MartÃnez-Alonso, Marcos Malumbres
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Cell Cycle | Cell Cycle: DNA Damage Checkpoints
Encyclopedia of Biological Chemistry III, 2021M. Weitzman +2 more
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A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
Nature, 1993M. Serrano, G. Hannon, D. Beach
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