Results 191 to 200 of about 812,761 (308)

Microneedles at the Forefront of Next Generation Theranostics

Advanced Science, EarlyView.
The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang, Yuan Yang, Jiaqi Zhang, Hanrui Zhang, Qian Wang, Shengmei Ma, Pengfei Zhao, Zhou Li, Yuxin Liu   +8 more
wiley   +1 more source

Cell cycle, checkpoints and cancer [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2013
openaire   +1 more source

Cell cycle checkpoint factor p15^Ink4b is a novel regulator of osteoclast differentiation. [PDF]

Sci Rep
Tsuji S, Mizukami S, Sakamoto A, Takemoto K, Seto T, Uehara K, Yukata K, Sakai T, Iwaisako K, Takeda N, Yanai R, Asagiri M.   +11 more
europepmc   +1 more source

Zonated Copper‐Driven Breast Cancer Progression Countered by a Copper‐Depleting Nanoagent for Immune and Metabolic Reprogramming

Advanced Science, EarlyView.
Spatially resolved multiomics reveals that high‐copper zones are closely associated with tumor metastasis, immune‐desert phenotypes, and oxidative‐phosphorylation (OXPHOS)‐dependent proliferation. A targeted bacterial nanovesicle delivering copper‐depleting agents effectively reduces tumor copper levels, inhibits OXPHOS‐dependent tumor growth, and ...
Lin Chen, Saibo Ma, Hao Wu, Lingna Zheng, Yunpeng Yi, Guangnian Liu, Baoyi Li, Jiayi Sun, Yang Du, Bing Wang, Yike Liu, Cheng Zhang, Jing Chang, Yuheng Pang, Wenjing Wang, Meng Wang, Motao Zhu   +16 more
wiley   +1 more source

Orchestration of DNA Damage Checkpoint Dynamics across the Human Cell Cycle.

Cell Systems, 2017
H. Chao, Cere E. Poovey, Ashley A. Privette, Gavin D. Grant, Hui Yan Chao, J. Cook, J. Purvis   +6 more
semanticscholar   +1 more source

Author Correction: TOP2A inhibition and its cellular effects related to cell cycle checkpoint adaptation pathway. [PDF]

Sci Rep
Arroyo M, Fernández-Mimbrera MA, Gollini E, Esteve-Codina A, Sánchez A, Marchal JA.   +5 more
europepmc   +1 more source

Erratum: Sp1 Contributes to Radioresistance of Cervical Cancer Through Targeting G2/M Cell Cycle Checkpoint CDK1 [Corrigendum]. [PDF]

Cancer Manag Res, 2021
europepmc   +1 more source

SIRT4 Promotes Pancreatic Cancer Stemness by Enhancing Histone Lactylation and Epigenetic Reprogramming Stimulated by Calcium Signaling

Advanced Science, EarlyView.
As a downstream target of α2δ1‐mediated calcium signaling, SIRT4 serves as an oncogene to promote the stemness of pancreatic cancer via deacetylating ENO1 directly at K358, leading to attenuated ENO1's RNA‐binding capacity, enhanced glycolytic substrate 2‐PG binding and robust glycolytic activity to increase the level of lactate that induce histone ...
Mengzhu Lv, Xiaodan Yang, Congcong Xu, Qingru Song, Hailian Zhao, Tianjiao Sun, Jingtao Liu, Yuan Zhang, Guogui Sun, Yuanchao Xue, Zhiqian Zhang   +10 more
wiley   +1 more source

Transmembrane and Immunoglobulin Domain Containing 1, a Putative Tumor Suppressor, Induces G2/M Cell Cycle Checkpoint Arrest in Colon Cancer Cells. [PDF]

Am J Pathol, 2021
De La Cena KOC, Ho RX, Amraei R, Woolf N, Tashjian JY, Zhao Q, Richards S, Walker J, Huang J, Chitalia VC, Rahimi N.   +10 more
europepmc   +1 more source