TAF15 mediates ROP16-induced apoptosis and cell cycle arrest in lung cancer
Parasites & VectorsObjective This study aimed to investigate the effects of the interaction between ROP16 and TAF15 on apoptosis and cell cycle regulation in A549 lung adenocarcinoma cells.
Guangqi Li +6 more
doaj +1 more source
A Method for Analyzing the Ubiquitination and Degradation of Aurora-A
Biological Procedures Online, 2002 The cell cycle machinery consists of regulatory proteins that control the progression through the cell cycle ensuring that DNA replication alternates with DNA segregation in mitosis to maintain cell integrity.
Klotzbucher Andrea +3 more
doaj +1 more source
Deep learning tools and modeling to estimate the temporal expression of cell cycle proteins from 2D still images. [PDF]
PLoS Comput Biol, 2022 Pécot T +4 more
europepmc +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Yeast UBL-UBA proteins have partially redundant functions in cell cycle control
Cell Division, 2006 Background Proteins containing ubiquitin-like (UBL) and ubiquitin associated (UBA) domains have been suggested to shuttle ubiquitinated substrates to the proteasome for degradation. There are three UBL-UBA containing proteins in budding yeast: Ddi1, Dsk2
Clarke Duncan J +3 more
doaj +1 more source
Curcumin Sensitises Cancerous Kidney Cells to TRAIL Induced Apoptosis via Let-7C Mediated Deregulation of Cell Cycle Proteins and Cellular Metabolism. [PDF]
Int J Mol Sci, 2022 Obaidi I +2 more
europepmc +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
A role for homologous recombination proteins in cell cycle regulation
, 2015 Eukaryotic cells respond to DNA breaks, especially double-stranded breaks (DSBs), by activating the DNA damage response (DDR), which encompasses DNA repair and cell cycle checkpoint signaling.
Nicolas Mermod (8282) +11 more
core +1 more source
Acta Crystallographica Section A Foundations of Crystallography, 1996 M. E. Noble +8 more
openaire +1 more source
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
FEBS Letters, EarlyView.Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source