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Methods in enzymology, 2008
Granzymes are cell death-inducing serine proteases released from cytotoxic granules of cytotoxic T lymphocytes and natural killer cells during granule exocytosis in response to viral infection or against transformed cells marked for elimination. A critical cofactor for the granule exocytosis pathway is perforin, which mediates the entry of granzymes ...
Martinvalet, Denis +2 more
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Granzymes are cell death-inducing serine proteases released from cytotoxic granules of cytotoxic T lymphocytes and natural killer cells during granule exocytosis in response to viral infection or against transformed cells marked for elimination. A critical cofactor for the granule exocytosis pathway is perforin, which mediates the entry of granzymes ...
Martinvalet, Denis +2 more
openaire +3 more sources
Blocking cell death to enhance cell death
Science Translational Medicine, 2017Inhibiting caspase activation during apoptosis may enhance the ability of the immune system to target cancer cells.
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A guide to cell death pathways
Nature Reviews Molecular Cell Biology, 2023Junying Yuan, Dimitry Ofengeim
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Roles of RIPK1 as a stress sentinel coordinating cell survival and immunogenic cell death
Nature Reviews Molecular Cell Biology, 2023Jarama Clucas, Pascal Meier
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Emerging connectivity of programmed cell death pathways and its physiological implications
Nature Reviews Molecular Cell Biology, 2020Sammy Bedoui +2 more
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