Results 171 to 180 of about 3,307,555 (359)

Pathophysiology of ischemic cell death: II. Changes in plasma membrane permeability and cell volume. [PDF]

, 1983
A. Ames, Frances B. Nesbett
openalex   +1 more source

Cell death and senescence

Journal of Translational Medicine, 2023
Lorenzo Galluzzi, Melissa Myint
openaire   +3 more sources

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

ALTERATIONS IN CELLULAR METABOLISM ASSOCIATED WITH CELL DEATH INDUCED BY URACIL MUSTARD AND 6-THIOGUANINE

, 1964
Barbara A. Booth, William A. Creasey, Alan C. Sartorelli   +2 more
openalex   +1 more source

Causes of death in sickle-cell disease in Jamaica. [PDF]

, 1982
A N Thomas, C. W. Pattison, G. R. Serjeant   +2 more
openalex   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Topographic targeting errors in the retinocollicular projection and their elimination by selective ganglion cell death [PDF]

, 1986
DD O'Leary, J W Fawcett, Wm Cowan
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

CDC25A inhibition sensitizes melanoma cells to doxorubicin and NK cell therapy

Cell Death and Disease
Cell division cycle 25 (CDC25) phosphatases serve as crucial regulators of cell cycle phase transitions and essential components of the checkpoint machinery involved in DNA damage response.
Xinyue Gao, Feichang Liu, Bo Zhang, Tianyi Ren, You Zheng, Zubiao Niu, He Ren, Chenyu Liu, Chengzuo Jiang, Chenxi Wang, Hongyan Huang, Li Ma, Qiang Sun   +12 more
doaj   +1 more source

Inhibition of epithelial cell death in the secondary palate in vitro by alteration of lysosome function.

, 1978
Robert M. Greene, Robert M. Pratt
openalex   +1 more source