Results 251 to 260 of about 3,157,910 (364)

Programmed cell death of T lymphocytes during acute viral infection: a mechanism for virus-induced immune deficiency [PDF]

, 1993
Enal Razvi, Raymond M. Welsh
openalex   +1 more source

Programmed cell death protein 1 in cancer cells. [PDF]

Cell Commun Signal
Wei C, Liu M, Zhang W.
europepmc   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Accelerated programmed cell death (apoptosis) in erythroid precursors of patients with severe beta-thalassemia (Cooley's anemia) [see comments] [PDF]

, 1993
Jie Yuan, Emanuele Angelucci, Giuseppe Lucarelli, M Aljurf, LM Snyder, Kiefer Cr, L. Ma, SL Schrier   +7 more
openalex   +1 more source

Hyperammonemia induces programmed liver cell death. [PDF]

Sci Adv
Kerbert AJC, Engelmann C, Habtesion A, Kumar P, Hassan M, Qi T, Volkert I, Otto T, Hall A, Khetan VU, Olde Damink S, Aguilar F, Chollet C, Brunet L, Clària J, Moreau R, Arroyo V, Coenraad MJ, Mehta G, Castelli F, Trautwein C, Fenaille F, Andreola F, Jalan R.   +23 more
europepmc   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Cryptosporidium parvum infection of Caco-2 cell monolayers induces an apical monolayer defect, selectively increases transmonolayer permeability, and causes epithelial cell death [PDF]

, 1994
Jeffrey K. Griffiths, Robert B. Moore, Sean N. Dooley, Gerald T. Keusch, Saul Tzipori   +4 more
openalex   +1 more source

Cell Death and Senescence-Based Molecular Classification and an Individualized Prediction Model for Lung Adenocarcinoma. [PDF]

MedComm (2020)
Wang P, Zhang C, Wu P, Zhao Z, Sun N, Xue Q, Gao S, He J.   +7 more
europepmc   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

TMBIM6 INHIBITS APOPTOSIS OF VULNERABLE NEURONS IN PARKINSON´S DISEASE

IBRO Neuroscience Reports, 2023
Pablo Ahumada Montalva, Carolina Jerez, Sara Borquez, Francisco Muñoz, Melissa Nassif, Mario Sanhueza, Rene Vidal, Diego Rojas Rivera   +7 more
doaj