Results 271 to 280 of about 8,637,589 (310)
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Trends in Genetics, 1995
A novel oncogene-derived protein, Bcl-2, functions as a repressor of cell death in a genetic pathway of cellular suicide that appears to be common to all multicellular animals. A related protein that promotes cell death, Bax, wrestles with Bcl-2 through conserved motifs, BH1 and BH2, establishing a set point for these deaths.
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A novel oncogene-derived protein, Bcl-2, functions as a repressor of cell death in a genetic pathway of cellular suicide that appears to be common to all multicellular animals. A related protein that promotes cell death, Bax, wrestles with Bcl-2 through conserved motifs, BH1 and BH2, establishing a set point for these deaths.
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Current Opinion in Neurobiology, 1996
Apoptosis is a common feature of the nervous system, occurring physiologically during development and pathologically in several diseases. In view of the latter, pathways that regulate apoptosis in neurones are of particular interest, and recent advances in this field implicate several signalling pathways in the induction of apoptosis, after withdrawal ...
A, Fraser, N, McCarthy, G I, Evan
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Apoptosis is a common feature of the nervous system, occurring physiologically during development and pathologically in several diseases. In view of the latter, pathways that regulate apoptosis in neurones are of particular interest, and recent advances in this field implicate several signalling pathways in the induction of apoptosis, after withdrawal ...
A, Fraser, N, McCarthy, G I, Evan
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Phosphatidylcholine and cell death
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2002Phosphatidylcholine (PC) constitutes a major portion of cellular phospholipids and displays unique molecular species in different cell types and tissues. Inhibition of the CDP-choline pathway in most mammalian cells or overexpression of the hepatic phosphatidylethanolamine methylation pathway in hepatocytes leads to perturbation of PC homeostasis ...
Cui, Z., Houweling, M.
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Nature Cell Biology
Mitochondria are cellular factories for energy production, calcium homeostasis and iron metabolism, but they also have an unequivocal and central role in intrinsic apoptosis through the release of cytochrome c. While the subsequent activation of proteolytic caspases ensures that cell death proceeds in the absence of collateral inflammation, other ...
Hannah L. Glover +3 more
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Mitochondria are cellular factories for energy production, calcium homeostasis and iron metabolism, but they also have an unequivocal and central role in intrinsic apoptosis through the release of cytochrome c. While the subsequent activation of proteolytic caspases ensures that cell death proceeds in the absence of collateral inflammation, other ...
Hannah L. Glover +3 more
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Journal of Neurobiology, 1992
AbstractExcitotoxicity refers to the ability of glutamate or related excitatory amino acids to mediate the death of central neurons under certain conditions, for example, after intense exposure. Such excitotoxic neuronal death may contribute to the pathogenesis of brain or spinal cord injury associated with several human disease states.
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AbstractExcitotoxicity refers to the ability of glutamate or related excitatory amino acids to mediate the death of central neurons under certain conditions, for example, after intense exposure. Such excitotoxic neuronal death may contribute to the pathogenesis of brain or spinal cord injury associated with several human disease states.
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1998
Caspase is a recently proposed term for the ICE/CED-3 family of cysteine proteases (Alnemri et al. 1996). These proteases, which share the property of cleaving their substrates after an aspartate residue (aspase), first came to light when interleukin-lβ-converting enzyme (ICE) was cloned in 1992 (Cerretti et al. 1992; Thornberry et al. 1992).
L, Dorstyn, M, Kinoshita, S, Kumar
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Caspase is a recently proposed term for the ICE/CED-3 family of cysteine proteases (Alnemri et al. 1996). These proteases, which share the property of cleaving their substrates after an aspartate residue (aspase), first came to light when interleukin-lβ-converting enzyme (ICE) was cloned in 1992 (Cerretti et al. 1992; Thornberry et al. 1992).
L, Dorstyn, M, Kinoshita, S, Kumar
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A guide to cell death pathways
Nature Reviews Molecular Cell Biology, 2023Dimitry Ofengeim, Junying Yuan
exaly
Pore-forming proteins as drivers of membrane permeabilization in cell death pathways
Nature Reviews Molecular Cell Biology, 2022Geert Bultynck +2 more
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Programmed Cell Death or Cell Death Programme? That is the Question
Journal of Theoretical Biology, 2001D, Ratel +4 more
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