Results 191 to 200 of about 1,775,572 (317)

Directing stem cell differentiation by chromatin state approximation. [PDF]

Nucleic Acids Res
Montano-Gutierrez LF, Müller S, Kutschat AP, Adameyko I, Seruggia D, Halbritter F.   +5 more
europepmc   +1 more source

Differentiation of Chromaffin Cells

Journal of Pharmacy and Pharmacology, 1953
D M, SHEPHERD, G B, WEST
openaire   +2 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Correction: <i>Lmx1a</i> is essential for marginal cell differentiation and stria vascularis formation. [PDF]

Front Cell Dev Biol
Renauld JM, Iskusnykh IY, Yamoah EN, Smith RJH, Affortit C, He DZ, Liu H, Nichols D, Bouma J, Nayak MK, Weng X, Qin T, Sham MH, Chizhikov VV, Fritzsch B.   +14 more
europepmc   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Proteostasis sustains T cell differentiation potential and tumor-infiltrating lymphocyte function. [PDF]

Cell
Scharping NE, Ge X, Matias MI, Jiang F, Cafferata A, Heeg M, Monell A, Galletti G, Cheung KP, Rock A, Thao N, Shuttleworth SL, Bauer MA, Takehara KK, Ferry A, Quon S, Koss B, Myers SA, Bennett EJ, Goldrath AW.   +19 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Interleukin-4-producing type 2 innate lymphoid cells in the lymph node promote proallergic Tfh13 cell differentiation. [PDF]

Immunity
Lee D, Lu MP, Rajamanimuthu P, Das M, Ferraj E, Fisher C, Matatia P, Chen CW, Geha RS, Sokol CL, Gowthaman U.   +10 more
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

APN Inhibitor Bestatin Induces MM Cell Differentiation Through the CD79B/BTK/STAT3 Pathway. [PDF]

Cells
Wang X, Fang C, Li S, Zeng H, Liu J, Duan X, Zhang X, Jiang W, Wang X.   +8 more
europepmc   +1 more source