Results 221 to 230 of about 2,690,374 (356)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Ascorbic acid attenuates immunosenescence and cognitive decline via MYH9-Mediated CD8⁺ T cell differentiation. [PDF]

Immun Ageing
Mi T, Yang S, Wang N, Huo F, Zhao M, Lv S, Su T, Feng S, Wang H, Guo L, Zhu JK, Liu H.   +11 more
europepmc   +1 more source

Long-Term Survival and Differentiation of Human Neural Stem Cells in Nonhuman Primate Brain with no Immunosuppression

, 2015
Sang‐Rae Lee, Hong J. Lee, Sang-Hoon Cha, Kang-Jin Jeong, Youngjeon Lee, Chang‐Yeop Jeon, Kyung Sik Yi, Inja Lim, Zang‐Hee Cho, Kyu‐Tae Chang, Seung Up Kim   +10 more
openalex   +2 more sources

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

The evolution of irreversible cell differentiation under cell death effect. [PDF]

PLoS One
Gao Y, Zhao X, Li C.
europepmc   +1 more source

Mifepristone-Inducible Caspase-1 Expression in Mouse Embryonic Stem Cells Eliminates Tumor Formation but Spares Differentiated Cells In Vitro and In Vivo [PDF]

, 2011
Yi Wang, Dehua Yang, Lin Song, Ting Li, Juan Yang, Xiaojie Zhang, Weidong Le   +6 more
openalex   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Differentiation of Pancreatic Acinar Cells to Hepatocytes Requires an Intermediate Cell Type [PDF]

, 2010
Sung–Yu Wu, Chi–Che Hsieh, Ruei–Ren Wu, Jimmy Susanto, Tsung–Ta Liu, Chia‐Rui Shen, Yu Chen, Chien–Chang Su, Fang‐Pei Chang, Hsiao–Min Chang, David Tosh, Chia‐Ning Shen   +11 more
openalex   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

RUNX1 expression dynamics in plasma cell differentiation and pathogenesis of multiple myeloma. [PDF]

Front Immunol
Tang TF, Chan YT, Lim HJ, Cheok YY, Anuar NA, Cheong CS, Looi CY, Tan SM, Wong WF, Gan GG.   +9 more
europepmc   +1 more source