Results 231 to 240 of about 20,962,508 (350)

Tumors mimic the niche to inhibit neighboring stem cell differentiation. [PDF]

Elife
Zhang Y, Wang Y, Song J, Yan L, Wang Z, Song D, Wang H, Yang S, Niu L, Sun C, Zhang H, Zhao Y, Zhao S.   +12 more
europepmc   +1 more source

Ketogenesis contributes to intestinal cell differentiation

Cell Death and Differentiation, 2016
Qing-Ding Wang, Yuning Zhou, P. Rychahou, T. Fan, A. Lane, H. Weiss, B. Evers   +6 more
semanticscholar   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Dendritic cell circadian clocks shape memory CD8⁺ T cell differentiation. [PDF]

Sci Adv
Vleeshouwers W, van Duikeren S, de Graaf JF, Veerkamp DMB, Linger ME, Jorritsma SHT, Myeni SK, Kervezee L, Arens R.   +8 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Expression and Role of the RNA-Binding Protein, ZFP36L1, in Mouse T Follicular Helper Cell Differentiation and Function. [PDF]

Eur J Immunol
Carslaw HA, Woolliscroft S, Watson EM, Bell SE, Linterman MA, Turner M, Webb LMC.   +6 more
europepmc   +1 more source

TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function

Nature, 2008
Liang Zhou, Jared E. Lopes, M. Chong, I. Ivanov, Roy Min, G. Victora, Yue-Lei Shen, Jian-Guang Du, Y. P. Rubtsov, A. Rudensky, S. Ziegler, D. Littman   +11 more
semanticscholar   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Expression of Concern: Hyaluronan Is Crucial for Stem Cell Differentiation into Smooth Muscle Lineage. [PDF]

Stem Cells
europepmc   +1 more source