Results 251 to 260 of about 1,782,327 (317)

Mapping metabolic reprogramming dynamics across pancreatic neuroendocrine tumor cell differentiation at single-cell transcriptomic resolution. [PDF]

Front Genet
Yu P, Xiao J.
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Regulatory mechanisms of Th9 cell differentiation. [PDF]

Front Immunol
Liu X, Li Y, Wu W, Huang H, Hao Y, Song C.   +5 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

KLF2 overrides the resident memory CD8 T cell differentiation program, in opposition to KLF3. [PDF]

Proc Natl Acad Sci U S A
DePauw TA, Gai K, Shen J, Maurice NJ, Rhee KH, Valente WJ, O'Connor CH, Cui W, Peng C, Jameson SC.   +9 more
europepmc   +1 more source

Shaping Cell Identity: Global Transcriptome and Pathway Shifts during Mouse Mammary Epithelial Cell Differentiation. [PDF]

Comput Struct Biotechnol J
Ahmad W, Panicker NG, Rizvi TA, Mustafa F.   +3 more
europepmc   +1 more source

Impact of C4BPA on Muscle progenitor cell differentiation: insights for Duchenne muscular dystrophy treatment. [PDF]

Cell Death Dis
Fernández-Simón E, Tejedera-Villafranca A, Fernández-Garabay X, Clark J, Katsikis P, Mehra P, Galloway A, Monceau A, Villalobos E, Cox D, Ramón-Azcón J, Fernández-Costa JM, Díaz-Manera J.   +12 more
europepmc   +1 more source

Follicular helper-like γδ T cells promote plasma cell differentiation in Behçet's disease. [PDF]

Front Immunol
Mohammed SS, Alkhalifah AKS, Mirza R, Okinedo SO, Inampudi RA, Bibi A, Senusi A, Pardieu C, McCarthy NE, Fortune F, Flores-Borja F.   +10 more
europepmc   +1 more source

Single-cell landscape of goose thymus uncovers developmental and regulatory dynamics of T cell differentiation. [PDF]

Poult Sci
Wang C, Zhu Z, Liu Y, Yang Y, Chen S, He D.   +5 more
europepmc   +1 more source

Asymmetry and redundancy of STAT5 paralogs across CD8⁺ T cell differentiation states. [PDF]

Commun Biol
Ristin S, Dalzell M, Armstrong C, Ilsin N, Fontanella AM, Nivelo L, Hennighausen L, O'Shea JJ, Villarino AV.   +8 more
europepmc   +1 more source