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Osteoblastic cells: Differentiation and trans-differentiation

Archives of Biochemistry and Biophysics, 2008
The osteoblast is the bone forming cell and is derived from mesenchymal stem cells (MSC) present among the bone marrow stroma. MSC are capable of multi-lineage differentiation into mesoderm-type cells such as osteoblasts and adipocytes. Understanding the mechanisms underlying osteoblast differentiation from MSC is a central topic in bone biology that ...
Kassem, Moustapha   +2 more
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Differentiation of B-cells

1995
B-cell develop their B-cell receptor (BCR) via transient formation of surrogate L-chain/p55 complexes.
H.-Harald Sedlacek, Tarik Möröy
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Cell Differentiation and Malignancy

Cell Biophysics, 1986
An understanding of the mechanism that controls growth and differentiation in normal cells would seem to be an essential requirement to elucidate the origin and reversibility of malignancy. For this approach I have mainly used normal and leukemic blood cells, and in most studies have used myeloid blood cells as a model system.
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Erythroid Cell Differentiation

1976
We have reviewed erythroid cell differentiation from two points of view: 1) differences between fetal and adult human red cells with particular reference to alterations which can occur in the normal pattern of erythroid cell development during the course of leukemia; 2) beochemical events which occur during erythroid cell maturation, as a model system ...
B G, Forget, J, Glass, D, Housman
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Muscle cell differentiation

Current Opinion in Cell Biology, 1989
The appeal of myogenic differentiation as a model developmental system derives in part from the complexity of regulatory steps required to account for the diversity of muscle structure and function. The intricate patterns of contractile tissue formation in the adult animal depend on the orderly progression of molecular signals that lead primordial ...
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Glycolipids and Cell Differentiation

1980
Differentiation of a cultured cell refers generally to a change in the expression of some peculiar functions specific to this cell. Generally differentiation involves only a modification of some biochemical properties of the cell such as synthesis of melanin by melanocytes (KREIDER et al., 1975) or synthesis of collagen by bone fibroblasts (MANNER and ...
G, Rebel, J, Robert, P, Mandel
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Erythroid cell differentiation

Molecular and Cellular Biochemistry, 1978
Normal and transformed erythroid cell precursors provide the opportunity for study of a number of problems relevant to the regulation of proliferation and differentiation in a developmental system. Evidence is presented which suggests that the hormone, erythropoietin, has a primary role in regulating precursor cell proliferation.
M, Terada, P A, Marks, R A, Rifkind
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Differentiation of PC12 Cells

Science's STKE, 2006
This 3-week-long series of collaborative laboratory exercises explores how to use a cultured cell system (PC12 cells) to study signaling pathways involved in cellular differentiation. The laboratory would be useful in a neurobiology or cell biology course for advanced undergraduate students.
Elizabeth M, Adler   +2 more
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Synchronous Cell Differentiation

1968
Publisher Summary Synchronous cell differentiation refers to the occurrence of simultaneous cellular transformations throughout a population of cells. Although the induction of cell division synchrony may be a prerequisite for such an experimental situation, it need not be the primary concern of the investigator.
G M, Padilla, I L, Cameron
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