Results 101 to 110 of about 12,176,123 (363)

Polo-like kinase 4: the odd one out of the family

open access: yesCell Division, 2010
Polo-like kinase 4 (PLK4) is a unique member of the Polo-like family of kinases that shares little homology with its siblings and has an essential role in centriole duplication.
Bornens Michel, Sillibourne James E
doaj   +1 more source

Cell Division Intersects with Cell Geometry [PDF]

open access: yesCell, 2010
Single-celled organisms monitor cell geometry and use this information to control cell division. Such geometry-sensing mechanisms control both the decision to enter into cell division and the physical orientation of the chromosome segregation machinery, suggesting that signals controlling cell division may be linked to the mechanisms that ensure proper
Paul Nurse, James B. Moseley
openaire   +3 more sources

Centrosomes in asymmetric cell division [PDF]

open access: yesCurrent Opinion in Structural Biology, 2021
Asymmetric cell division (ACD) is a strategy for achieving cell diversity. Research carried out over the last two decades has shown that in some cell types that divide asymmetrically, mother and daughter centrosomes are noticeably different from one another in structure, behaviour, and fate, and that robust ACD depends upon centrosome function. Here, I
openaire   +4 more sources

Stem cell decisions:A twist of fate or a niche market? [PDF]

open access: yes, 2014
Establishing and maintaining cell fate in the right place at the right time is a key requirement for normal tissue maintenance. Stem cells are at the core of this process.
Anderson   +112 more
core   +2 more sources

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Human linker histones: interplay between phosphorylation and O-β-GlcNAc to mediate chromatin structural modifications

open access: yesCell Division, 2011
Eukaryotic chromatin is a combination of DNA and histone proteins. It is established fact that epigenetic mechanisms are associated with DNA and histones.
Nazar Shazia   +5 more
doaj   +1 more source

Development and validation of a two glycolysis-related LncRNAs prognostic signature for glioma and in vitro analyses

open access: yesCell Division, 2023
Background Mounting evidence suggests that there is a complex regulatory relationship between long non-coding RNAs (lncRNAs) and the glycolytic process during glioma development.
Xiaoping Xu   +5 more
doaj   +1 more source

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

open access: yesFEBS Letters, EarlyView.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet   +4 more
wiley   +1 more source

Phasing in on the cell cycle

open access: yesCell Division, 2018
Just like all matter, proteins can also switch between gas, liquid and solid phases. Protein phase transition has claimed the spotlight in recent years as a novel way of how cells compartmentalize and regulate biochemical reactions.
Steven Boeynaems   +2 more
doaj   +1 more source

Role of microRNAs in regulation of doxorubicin and paclitaxel responses in lung tumor cells

open access: yesCell Division, 2023
Lung cancer as the leading cause of cancer related mortality is always one of the main global health challenges. Despite the recent progresses in therapeutic methods, the mortality rate is still significantly high among lung cancer patients. A wide range
Amirhosein Maharati, Meysam Moghbeli
doaj   +1 more source

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