Results 121 to 130 of about 12,176,123 (363)
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
MicroRNAs’ control of cancer cell dormancy
Cell Division, 2019 ‘Dormancy’, in the context of carcinogenesis, is a biological phenomenon of decreased cancer cell proliferation and metabolism. In view of their ability to remain quiescent, cancer cells are able to avoid cell death induced by chemotherapeutic agents ...
Tatiana G. Ruksha
doaj +1 more source
A Simple Model of Cell Proliferation of Bacteria Using Min Oscillation [PDF]
, 2019 A mathematical model of Min oscillation in Escherichia coli is numerically studied. The oscillatory state and hysteretic transition are explained with simpler coupled differential equations. Next, we propose a simple model of cell growth and division using the Min oscillation. The cell cycle is not constant but exhibits fluctuation in the deterministic
arxiv +1 more source
The physiology of bacterial cell division
Annals of the New York Academy of Sciences, 2013 Bacterial cell division is facilitated by the divisome, a dynamic multiprotein assembly localizing at mid‐cell to synthesize the stress‐bearing peptidoglycan and to constrict all cell envelope layers.
A. Egan, W. Vollmer
semanticscholar +1 more source
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
Protein arginine methylation: an emerging regulator of the cell cycle
Cell Division, 2018 Protein arginine methylation is a common post-translational modification where a methyl group is added onto arginine residues of a protein to alter detection by its binding partners or regulate its activity.
Anita E. Raposo, Sabine C. Piller
doaj +1 more source
Selection for synchronized cell division in simple multicellular organisms [PDF]
arXiv, 2018 The evolution of multicellularity was a major transition in the history of life on earth. Conditions under which multicellularity is favored have been studied theoretically and experimentally. But since the construction of a multicellular organism requires multiple rounds of cell division, a natural question is whether these cell divisions should be ...
arxiv
A Localized Wnt Signal Orients Asymmetric Stem Cell Division in Vitro
Science, 2013 Stem cells orient cell division and generate a distinct cell fate based on position relative to the Wnt source. Developmental signals such as Wnts are often presented to cells in an oriented manner.
Shukry J. Habib +6 more
semanticscholar +1 more source
Symbiotic Cell Differentiation and Cooperative Growth in Multicellular Aggregates
, 2016 As cells grow and divide under a given environment, they become crowded and resources are limited, as seen in bacterial biofilms and multicellular aggregates.
Kaneko, Kunihiko +2 more
core +2 more sources
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source