Results 101 to 110 of about 15,182,492 (337)

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The chromosomal passenger complex and the spindle assembly checkpoint: kinetochore-microtubule error correction and beyond

Cell Division, 2008
During mitosis, correct bipolar chromosome attachment to the mitotic spindle is an essential prerequisite for the equal segregation of chromosomes. The spindle assembly checkpoint can prevent chromosome segregation as long as not all chromosome pairs ...
Maia André F, Vader Gerben, Lens Susanne MA   +2 more
doaj   +1 more source

Intertwined Functions of Separase and Caspase in Cell Division and Programmed Cell Death. [PDF]

, 2020
Timely sister chromatid separation, promoted by separase, is essential for faithful chromosome segregation. Separase is a member of the CD clan of cysteine proteases, which also includes the pro-apoptotic enzymes known as caspases.
Jeong, Pan Young, Joshi, Pradeep M, Kumar, Ashish, Rothman, Joel H   +3 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

CIP/KIP and INK4 families as hostages of oncogenic signaling

Cell Division
CIP/KIP and INK4 families of Cyclin-dependent kinase inhibitors (CKIs) are well-established cell cycle regulatory proteins whose canonical function is binding to Cyclin-CDK complexes and altering their function.
Lucia Csergeová, David Krbušek, Radoslav Janoštiak   +2 more
doaj   +1 more source

The many faces of ubiquitinated histone H2A: insights from the DUBs

Cell Division, 2008
Monoubiquitination of H2A is a major histone modification in mammalian cells. Understanding how monoubiquitinated H2A (uH2A) regulates DNA-based processes in the context of chromatin is a challenging question.
Di Fiore Pier, van Lohuizen Maarten, Nicassio Francesco, Vissers Joseph HA, Citterio Elisabetta   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Branching Feller diffusion for cell division with parasite infection

, 2010
We describe the evolution of the quantity of parasites in a population of cells which divide in continuous-time. The quantity of parasites in a cell follows a Feller diffusion, which is splitted randomly between the two daughter cells when a division ...
Bansaye, Vincent, Tran, Viet Chi
core   +1 more source

Protein Pattern Formation

, 2018
Protein pattern formation is essential for the spatial organization of many intracellular processes like cell division, flagellum positioning, and chemotaxis.
A Desai, A Melbinger, A Touhami, A Treuner-Lange, A Varma, A-C Butty, AB Goryachev, AG Vecchiarelli, AJ Molendijk, AM Turing, B Goldstein, B Klünder, BD Corbin, D Schumacher, D Thalmeier, DA Ramirez-Diaz, David Fange, DM Raskin, DM Raskin, E Bi, E Mileykovskaya, E Munro, F Wu, Fabai Wu, FO Bendezu, G Bange, G Meacci, I Bose, IS Aranson, J Denk, J Denk, J Guckenheimer, J Halatek, J Halatek, J Halatek, J Halatek, J Lutkenhaus, J Lutkenhaus, J Männik, J Schweizer, JE Pearson, JS Schuhmacher, K Gerdes, K Zieske, K Zieske, K Zieske, K-T Park, KC Huang, KJ Lee, L Kozubowski, L Laan, L Reese, L Reese, LA Segel, LD Renner, LL Lackner, M Bonny, M Cross, M Kac, M Loose, M Loose, M Loose, M Loose, M Otsuji, MC Florian, NW Goehring, NW Goehring, NW Goehring, O Sliusarenko, P Gray, P Gray, P Gray, R Thom, R Wedlich-Soldner, RA Green, S Bergeler, S Kondo, S Kretschmer, T Freisinger, TH Szeto, V Ivanov, V Varga, V Varga, WM Bement, Y Caspi, Y Gu, Y-L Shih, Y-L Shih, Y-L Shih, Z Hu, Z Hu, Z Hu, Z Hu, Z Hu   +93 more
core   +1 more source