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FEBS Letters, 2007 Cell–cell fusion is a highly regulated and dramatic cellular event that is required for development and homeostasis. Fusion may also play a role in the development of cancer and in tissue repair by stem cells. While virus–cell fusion and the fusion of intracellular membranes have been the subject of intense investigation during the past decade, cell ...
Elizabeth Chen
exaly +4 more sources
Flagging fusion: Phosphatidylserine signaling in cell–cell fusion [PDF]
Journal of Biological Chemistry, 2021 Formations of myofibers, osteoclasts, syncytiotrophoblasts, and fertilized zygotes share a common step, cell-cell fusion. Recent years have brought about considerable progress in identifying some of the proteins involved in these and other cell-fusion processes.
Jarred M. Whitlock +1 more
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Confusion on Cell Fusion [PDF]
Cellular and Molecular Gastroenterology and Hepatology, 2021 Cell fusion, whereby two cells merge to create one, has been widely described in development, but the role of cell fusion in tissue regeneration and homeostasis remains an open debate. We propose that the regenerative capacity of the gut can be fully attributed to extensive plasticity of the intestinal epithelium.
Ramadan, Rana, Vermeulen, Louis
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Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion
eLife, 2022 TMEM16F, a Ca2+-activated phospholipid scramblase (CaPLSase), is critical for placental trophoblast syncytialization, HIV infection, and SARS-CoV2-mediated syncytialization, however, how TMEM16F is activated during cell fusion is unclear.
Yang Zhang +8 more
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Viruses, 2023 Human endogenous retrovirus type W (HERV-W) is expressed in various cancers. We previously developed an adenovirus-vectored cancer vaccine targeting HERV-W by encoding an assembled HERV-W group-specific antigen sequence and the HERV-W envelope sequence ...
Isabella Skandorff +7 more
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Generating Heterokaryotic Cells via Bacterial Cell-Cell Fusion
Microbiology Spectrum, 2022 Fusion of cells is an important and common biological process that leads to the mixing of cellular contents and the formation of multinuclear cells. Cell fusion occurs when distinct membranes are brought into proximity of one another and merge to become ...
Shraddha Shitut +7 more
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Cells, 2022 Cre/loxP recombination is a well-established technique increasingly used for modifying DNA both in vitro and in vivo. Nucleotide alterations can be edited in the genomes of mammalian cells, and genetic switches can be designed to target the expression or
Hsiang-Ching Tseng +3 more
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The hallmarks of cell-cell fusion [PDF]
Development, 2017 Cell-cell fusion is essential for fertilization and organ development. Dedicated proteins known as fusogens are responsible for mediating membrane fusion. However, until recently, these proteins either remained unidentified or were poorly understood at the mechanistic level. Here, we review how fusogens surmount multiple energy barriers to mediate cell-
Javier M. Hernández +1 more
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Preparation of Monoclonal Antibody against Deoxynivalenol and Development of Immunoassays
Toxins, 2022 Fusarium toxins are the largest group of mycotoxins, which contain more than 140 known secondary metabolites of fungi. Deoxynivalenol (DON) is one of the most important compounds of this class due to its high toxicity and its potential to harm mankind ...
Hoyda Elsir Mokhtar +4 more
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WHI-2 Regulates Intercellular Communication via a MAP Kinase Signaling Complex
Frontiers in Microbiology, 2020 The formation of the fungal mycelial network is facilitated by somatic cell fusion of germinating asexual spores (or germlings). Neurospora crassa germlings in close proximity display chemotropic growth that is dependent upon an intracellular network of ...
A. Pedro Gonçalves +4 more
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