Results 1 to 10 of about 1,377,302 (248)

WHI-2 Regulates Intercellular Communication via a MAP Kinase Signaling Complex [PDF]

Frontiers in Microbiology, 2020
The formation of the fungal mycelial network is facilitated by somatic cell fusion of germinating asexual spores (or germlings). Neurospora crassa germlings in close proximity display chemotropic growth that is dependent upon an intracellular network of ...
A. Pedro Gonçalves, Karen M. Chow, Sara Cea-Sánchez, N. Louise Glass, N. Louise Glass   +4 more
doaj   +4 more sources

The Zinc Finger Protein Zfp2 Regulates Cell–Cell Fusion and Virulence in Cryptococcus neoformans [PDF]

Journal of Fungi
Cryptococcus neoformans is a fungal pathogen commonly found in the environment. It mainly infects immunocompromised individuals, causing cryptococcal pneumonia and meningitis, which result in hundreds of thousands of deaths each year.
Cheng-Li Fan, Lin Li, Ji-Chong Shi, Tong-Bao Liu   +3 more
doaj   +2 more sources

Separate, separated, and together: the transcriptional program of the Clostridium acetobutylicum-Clostridium ljungdahlii syntrophy leading to interspecies cell fusion [PDF]

mSystems
Syntrophic cocultures (hitherto assumed to be commensalistic) of Clostridium acetobutylicum and Clostridium ljungdahlii, whereby CO2 and H2 produced by the former feed the latter, result in interspecies cell fusion involving large-scale exchange of ...
Noah B. Willis, Eleftherios T. Papoutsakis   +1 more
doaj   +2 more sources

Cell fusion as a driver of metastasis: re-evaluating an old hypothesis in the age of cancer heterogeneity [PDF]

Frontiers in Immunology
Numerous studies have investigated the molecular mechanisms and signalling pathways underlying cancer metastasis, as there is still no effective treatment for this terminal stage of the disease.
Eduardo López-Collazo, Eduardo López-Collazo, Eduardo López-Collazo, Eduardo López-Collazo, Laura Hurtado-Navarro, Laura Hurtado-Navarro   +5 more
doaj   +2 more sources

Bone Marrow Myeloid-Lymphatic Progenitors Expand Tumor Lymphatic Vasculature Through Cell Fusion. [PDF]

Cancers (Basel)
Athaiya S, Volk-Draper L, Cox E, Robinson K, Zinkevich N, Ran S.   +5 more
europepmc   +3 more sources

Role of glycosylation mutations at the N-terminal domain of SARS-CoV-2 XEC variant in immune evasion, cell-cell fusion, and spike stability. [PDF]

J Virol
Li P, Faraone JN, Hsu CC, Chamblee M, Liu Y, Zheng Y-M, Xu Y, Carlin C, Horowitz JC, Mallampalli RK, Saif LJ, Oltz EM, Jones D, Li J, Gumina RJ, Bednash JS, Xu K, Liu S-L.   +17 more
europepmc   +2 more sources

Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion

eLife, 2022
TMEM16F, a Ca2+-activated phospholipid scramblase (CaPLSase), is critical for placental trophoblast syncytialization, HIV infection, and SARS-CoV2-mediated syncytialization, however, how TMEM16F is activated during cell fusion is unclear.
Yang Zhang, Pengfei Liang, Liheng Yang, Ke Zoe Shan, Liping Feng, Yong Chen, Wolfgang Liedtke, Carolyn B Coyne, Huanghe Yang   +8 more
doaj   +1 more source

The Insertion of an Evolutionary Lost Four-Amino-Acid Cytoplasmic Tail Peptide into a Syncytin-1 Vaccine Increases T- and B-Cell Responses in Mice

Viruses, 2023
Human endogenous retrovirus type W (HERV-W) is expressed in various cancers. We previously developed an adenovirus-vectored cancer vaccine targeting HERV-W by encoding an assembled HERV-W group-specific antigen sequence and the HERV-W envelope sequence ...
Isabella Skandorff, Jasmin Gille, Emeline Ragonnaud, Anne-Marie Andersson, Silke Schrödel, Christian Thirion, Ralf Wagner, Peter Johannes Holst   +7 more
doaj   +1 more source

Reciprocal t(9;22) ABL/BCR fusion proteins: leukemogenic potential and effects on B cell commitment [PDF]

, 2009
Background: t(9;22) is a balanced translocation, and the chromosome 22 breakpoints (Philadelphia chromosome – Ph+) determine formation of different fusion genes that are associated with either Ph+ acute lymphatic leukemia (Ph+ ALL) or chronic myeloid ...
Henschler, Reinhard, Moore, Malcolm A. S., Oancea, Claudia, Ruthardt, Martin, Zheng, Xiaomin   +4 more
core   +16 more sources

Generating Heterokaryotic Cells via Bacterial Cell-Cell Fusion

Microbiology Spectrum, 2022
Fusion of cells is an important and common biological process that leads to the mixing of cellular contents and the formation of multinuclear cells. Cell fusion occurs when distinct membranes are brought into proximity of one another and merge to become ...
Shraddha Shitut, Meng-Jie Shen, Bart Claushuis, Rico J. E. Derks, Martin Giera, Daniel Rozen, Dennis Claessen, Alexander Kros   +7 more
doaj   +1 more source