Results 1 to 10 of about 12,743,149 (341)

WHI-2 Regulates Intercellular Communication via a MAP Kinase Signaling Complex [PDF]

open access: yesFrontiers in Microbiology, 2020
The formation of the fungal mycelial network is facilitated by somatic cell fusion of germinating asexual spores (or germlings). Neurospora crassa germlings in close proximity display chemotropic growth that is dependent upon an intracellular network of ...
A. Pedro Gonçalves   +4 more
doaj   +4 more sources

Monocyte-Macrophage Lineage Cell Fusion. [PDF]

open access: yesInt J Mol Sci, 2022
Cell fusion (fusogenesis) occurs in natural and pathological conditions in prokaryotes and eukaryotes. Cells of monocyte–macrophage lineage are highly fusogenic.
Kloc M   +4 more
europepmc   +2 more sources

Requirement of myomaker-mediated stem cell fusion for skeletal muscle hypertrophy

open access: yeseLife, 2017
Fusion of skeletal muscle stem/progenitor cells is required for proper development and regeneration, however the significance of this process during adult muscle hypertrophy has not been explored.
Qingnian Goh, Douglas P Millay
doaj   +2 more sources

Cell Fusion-Related Proteins and Signaling Pathways, and Their Roles in the Development and Progression of Cancer

open access: yesFrontiers in Cell and Developmental Biology, 2022
Cell fusion is involved in many physiological and pathological processes, including gamete binding, and cancer development. The basic processes of cell fusion include membrane fusion, cytoplasmic mixing, and nuclear fusion.
Hao Zhang   +8 more
doaj   +2 more sources

The Zinc Finger Protein Zfp2 Regulates Cell–Cell Fusion and Virulence in Cryptococcus neoformans [PDF]

open access: yesJournal of Fungi
Cryptococcus neoformans is a fungal pathogen commonly found in the environment. It mainly infects immunocompromised individuals, causing cryptococcal pneumonia and meningitis, which result in hundreds of thousands of deaths each year.
Cheng-Li Fan   +3 more
doaj   +2 more sources

Separate, separated, and together: the transcriptional program of the Clostridium acetobutylicum-Clostridium ljungdahlii syntrophy leading to interspecies cell fusion [PDF]

open access: yesmSystems
Syntrophic cocultures (hitherto assumed to be commensalistic) of Clostridium acetobutylicum and Clostridium ljungdahlii, whereby CO2 and H2 produced by the former feed the latter, result in interspecies cell fusion involving large-scale exchange of ...
Noah B. Willis   +1 more
doaj   +2 more sources

Cell fusion as a driver of metastasis: re-evaluating an old hypothesis in the age of cancer heterogeneity [PDF]

open access: yesFrontiers in Immunology
Numerous studies have investigated the molecular mechanisms and signalling pathways underlying cancer metastasis, as there is still no effective treatment for this terminal stage of the disease.
Eduardo López-Collazo   +5 more
doaj   +2 more sources

SARS-CoV-2 and SARS-CoV Spike-Mediated Cell-Cell Fusion Differ in Their Requirements for Receptor Expression and Proteolytic Activation

open access: yesJournal of Virology, 2021
Cell-cell fusion allows viruses to infect neighboring cells without the need to produce free virus and contributes to tissue damage by creating virus-infected syncytia.
Bojan F. Hörnich   +7 more
semanticscholar   +1 more source

Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion

open access: yeseLife, 2022
TMEM16F, a Ca2+-activated phospholipid scramblase (CaPLSase), is critical for placental trophoblast syncytialization, HIV infection, and SARS-CoV2-mediated syncytialization, however, how TMEM16F is activated during cell fusion is unclear.
Yang Zhang   +8 more
doaj   +1 more source

The Insertion of an Evolutionary Lost Four-Amino-Acid Cytoplasmic Tail Peptide into a Syncytin-1 Vaccine Increases T- and B-Cell Responses in Mice

open access: yesViruses, 2023
Human endogenous retrovirus type W (HERV-W) is expressed in various cancers. We previously developed an adenovirus-vectored cancer vaccine targeting HERV-W by encoding an assembled HERV-W group-specific antigen sequence and the HERV-W envelope sequence ...
Isabella Skandorff   +7 more
doaj   +1 more source

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