Results 1 to 10 of about 12,947,661 (112)

SARS-CoV-2 and SARS-CoV Spike-Mediated Cell-Cell Fusion Differ in Their Requirements for Receptor Expression and Proteolytic Activation

open access: yesJournal of Virology, 2021
Cell-cell fusion allows viruses to infect neighboring cells without the need to produce free virus and contributes to tissue damage by creating virus-infected syncytia.
Anna Katharina Großkopf   +2 more
exaly   +2 more sources

Virus-Mediated Cell-Cell Fusion

open access: yesInternational Journal of Molecular Sciences, 2020
Cell-cell fusion between eukaryotic cells is a general process involved in many physiological and pathological conditions, including infections by bacteria, parasites, and viruses.
Lucie Bracq   +2 more
exaly   +2 more sources

Requirement of myomaker-mediated stem cell fusion for skeletal muscle hypertrophy

open access: yeseLife, 2017
Fusion of skeletal muscle stem/progenitor cells is required for proper development and regeneration, however the significance of this process during adult muscle hypertrophy has not been explored.
Qingnian Goh, Douglas P Millay
doaj   +2 more sources

Cell Fusion-Related Proteins and Signaling Pathways, and Their Roles in the Development and Progression of Cancer

open access: yesFrontiers in Cell and Developmental Biology, 2022
Cell fusion is involved in many physiological and pathological processes, including gamete binding, and cancer development. The basic processes of cell fusion include membrane fusion, cytoplasmic mixing, and nuclear fusion.
Hao Zhang   +8 more
doaj   +2 more sources

Cell Fusion: Merging Membranes and Making Muscle

open access: yesTrends in Cell Biology, 2019
Cell fusion is essential for the development of multicellular organisms, and plays a key role in the formation of various cell types and tissues.
Douglas Millay, Michael Petrany
exaly   +2 more sources

Flagging fusion: Phosphatidylserine signaling in cell–cell fusion

open access: yesJournal of Biological Chemistry, 2021
Formations of myofibers, osteoclasts, syncytiotrophoblasts, and fertilized zygotes share a common step, cell–cell fusion. Recent years have brought about considerable progress in identifying some of the proteins involved in these and other cell-fusion ...
Jarred M. Whitlock, L. Chernomordik
semanticscholar   +1 more source

Monocyte–Macrophage Lineage Cell Fusion

open access: yesInternational Journal of Molecular Sciences, 2022
Cell fusion (fusogenesis) occurs in natural and pathological conditions in prokaryotes and eukaryotes. Cells of monocyte–macrophage lineage are highly fusogenic.
M. Kloc   +4 more
semanticscholar   +1 more source

Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion

open access: yeseLife, 2022
TMEM16F, a Ca2+-activated phospholipid scramblase (CaPLSase), is critical for placental trophoblast syncytialization, HIV infection, and SARS-CoV2-mediated syncytialization, however, how TMEM16F is activated during cell fusion is unclear.
Yang Zhang   +8 more
doaj   +1 more source

The Insertion of an Evolutionary Lost Four-Amino-Acid Cytoplasmic Tail Peptide into a Syncytin-1 Vaccine Increases T- and B-Cell Responses in Mice

open access: yesViruses, 2023
Human endogenous retrovirus type W (HERV-W) is expressed in various cancers. We previously developed an adenovirus-vectored cancer vaccine targeting HERV-W by encoding an assembled HERV-W group-specific antigen sequence and the HERV-W envelope sequence ...
Isabella Skandorff   +7 more
doaj   +1 more source

Generating Heterokaryotic Cells via Bacterial Cell-Cell Fusion

open access: yesMicrobiology Spectrum, 2022
Fusion of cells is an important and common biological process that leads to the mixing of cellular contents and the formation of multinuclear cells. Cell fusion occurs when distinct membranes are brought into proximity of one another and merge to become ...
Shraddha Shitut   +7 more
doaj   +1 more source

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