Results 21 to 30 of about 12,374,157 (394)

Role of hypoxia in promoting migration and cell fusion of urine-derived stem cells

open access: yes陆军军医大学学报, 2023
Objective To explore the effect of hypoxia on cell migration and fusion of urine-derived stem cells (USCs) in vitro, and observe the changes in cytoskeleton and cell polarity during the process.
ZHANG Nannan, HU Chaoqun, HE Yun
doaj   +1 more source

Cell fusions in mammals [PDF]

open access: yesHistochemistry and Cell Biology, 2008
Cell fusions are important to fertilization, placentation, development of skeletal muscle and bone, calcium homeostasis and the immune defense system. Additionally, cell fusions participate in tissue repair and may be important to cancer development and progression.
Larsson, Lars-Inge   +2 more
openaire   +3 more sources

The anti‐HIV drug nelfinavir mesylate (Viracept) is a potent inhibitor of cell fusion caused by the SARSCoV‐2 spike (S) glycoprotein warranting further evaluation as an antiviral against COVID‐19 infections

open access: yesbioRxiv, 2020
Coronaviruses belong to a group of enveloped, positive-single stranded RNA viruses that are known to cause severe respiratory distress in animals and humans.
F. Musarrat   +5 more
semanticscholar   +1 more source

TAGLN2-Regulated Trophoblast Migration, Invasion and Fusion are Impaired in Preeclampsia

open access: yesFrontiers in Cell and Developmental Biology, 2022
Preeclampsia (PE) is a serious disease during pregnancy that affects approximately eight million mothers and infants worldwide each year and is closely related to abnormal trophoblast function.
Hao Wang   +10 more
doaj   +1 more source

Roles of cell fusion, hybridization and polyploid cell formation in cancer metastasis

open access: yesWorld Journal of Clinical Oncology, 2020
Cell-cell fusion is a normal biological process playing essential roles in organ formation and tissue differentiation, repair and regeneration. Through cell fusion somatic cells undergo rapid nuclear reprogramming and epigenetic modifications to form ...
I. Shabo   +7 more
semanticscholar   +1 more source

Tumor Hybrid Cells: Nature and Biological Significance

open access: yesFrontiers in Cell and Developmental Biology, 2022
Metastasis is the leading cause of cancer death and can be realized through the phenomenon of tumor cell fusion. The fusion of tumor cells with other tumor or normal cells leads to the appearance of tumor hybrid cells (THCs) exhibiting novel properties ...
Maria S. Tretyakova   +4 more
doaj   +1 more source

Cell Fusion

open access: yesDefinitions, 2020
A technique to form a single hybrid cell, by fusion of two or more dissimilar cells, either spontaneously or by induced fusion. The cells fuse and coalesce, but their nuclei may remain separated.

semanticscholar   +1 more source

A novel algorithm for finding optimal driver nodes to target control complex networks and its applications for drug targets identification

open access: yesBMC Genomics, 2018
Background The advances in target control of complex networks not only can offer new insights into the general control dynamics of complex systems, but also be useful for the practical application in systems biology, such as discovering new therapeutic ...
Wei-Feng Guo   +5 more
doaj   +1 more source

Filopodia powered by class x myosin promote fusion of mammalian myoblasts

open access: yeseLife, 2021
Skeletal muscle fibers are multinucleated cellular giants formed by the fusion of mononuclear myoblasts. Several molecules involved in myoblast fusion have been discovered, and finger-like projections coincident with myoblast fusion have also been ...
David W Hammers   +7 more
doaj   +1 more source

Cell–cell fusion

open access: yesFEBS Letters, 2007
Cell–cell fusion is a highly regulated and dramatic cellular event that is required for development and homeostasis. Fusion may also play a role in the development of cancer and in tissue repair by stem cells. While virus–cell fusion and the fusion of intracellular membranes have been the subject of intense investigation during the past decade, cell ...
Elizabeth H. Chen   +3 more
openaire   +3 more sources

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