Phagosome-lysosome fusion is a calcium-independent event in macrophages. [PDF]
, 1996 Phagosome-lysosome membrane fusion is a highly regulated event that is essential for intracellular killing of microorganisms. Functionally, it represents a form of polarized regulated secretion, which is classically dependent on increases in ...
Ernst, JD +5 more
core +2 more sources
A viral fusogen hijacks the actin cytoskeleton to drive cell-cell fusion
eLife, 2020 Cell-cell fusion, which is essential for tissue development and used by some viruses to form pathological syncytia, is typically driven by fusogenic membrane proteins with tall (>10 nm) ectodomains that undergo conformational changes to bring apposing
Ka Man Carmen Chan +3 more
doaj +1 more source
“Keep on rolling”: circulating cells in a botryllid ascidian torpor
Frontiers in Ecology and Evolution, 2023 Hemocytes of the colonial tunicate Botrylloides leachii play important roles throughout the animal’s life span, including transport and storage of nutrients, respiration, regeneration, budding, sexual reproduction, defense responses, and tunic generation.
Yosef Hyams +6 more
doaj +1 more source
The cell fusion-free vegetable list helps organic farmers to find suitable cultivars (Liveseed Practice Abstract) [PDF]
, 2019 You can download the list for free in German and French: https://www.fibl.org/en/shop-en/1671-zf-freie-sorten.html Further Information: FiBL breeding manual https://www.fibl.org/en/shop-en/1202-plant-breeding.html - IFOAM-strategy on artificial CMS
Kimmel, Thomas +2 more
core
Human Myoblast and Mesenchymal Stem Cell Interactions Visualized by Videomicroscopy. [PDF]
, 2015 Muscle-derived progenitor cell (myoblast) therapy has promise for the treatment of denervated, weakened, and fibrotic muscle. The best methods for injecting myoblasts to promote fusion and retention have yet to be determined, however.
Belafsky, Peter C +7 more
core +1 more source
Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano +7 more
wiley +1 more source
Neurospora crassa NADPH Oxidase NOX-1 Is Localized in the Vacuolar System and the Plasma Membrane
Frontiers in Microbiology, 2019 The NADPH oxidases (NOX) catalyze the production of superoxide by transferring electrons from NADPH to O2, in a regulated manner. In Neurospora crassa NOX-1 is required for normal growth of hyphae, development of aerial mycelium and asexual spores, and ...
Nallely Cano-Domínguez +3 more
doaj +1 more source
Massive NGS data analysis reveals hundreds of potential novel gene fusions in human cell lines [PDF]
, 2018 Background: Gene fusions derive from chromosomal rearrangements and the resulting chimeric transcripts are often endowed with oncogenic potential. Furthermore, they serve as diagnostic tools for the clinical classification of cancer subgroups with ...
Bolis, Marco +7 more
core +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
eLifeThe bone-resorbing activity of osteoclasts plays a critical role in the life-long remodeling of our bones that is perturbed in many bone loss diseases. Multinucleated osteoclasts are formed by the fusion of precursor cells, and larger cells – generated ...
Evgenia Leikina +5 more
doaj +1 more source