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Cell–cell fusion involves the fusion of somatic cells into a single hybrid cell. It is not only a physiological process but also an important cell engineering technology which can be applied to various fields, such as regenerative medicine, antibody ...
Chin Yang Chang +5 more
doaj +1 more source
FOntCell: Fusion of Ontologies of Cells [PDF]
High-throughput cell-data technologies such as single-cell RNA-seq create a demand for algorithms for automatic cell classification and characterization. There exist several cell classification ontologies with complementary information. However, one needs to merge them to synergistically combine their information.
Javier Cabau-Laporta +10 more
openaire +6 more sources
The cell fusion-free vegetable list helps organic farmers to find suitable cultivars (Liveseed Practice Abstract) [PDF]
You can download the list for free in German and French: https://www.fibl.org/en/shop-en/1671-zf-freie-sorten.html Further Information: FiBL breeding manual https://www.fibl.org/en/shop-en/1202-plant-breeding.html - IFOAM-strategy on artificial CMS
Kimmel, Thomas +2 more
core
Fusion of neurohypophyseal membranes in vitro [PDF]
Freeze cleaving electron microscopy has shown that fusion of isolated secretory vesicles from bovine neurohypophyses was induced by Ca 2+ in micromolar concentrations. Mg 2+ and Sr 2+ were ineffective. Mg 2+ inhibited Ca 2+-induced fusion. In suspensions
Dahl, G. +3 more
core +1 more source
Genetic basis of cell–cell fusion mechanisms [PDF]
Cell-cell fusion in sexually reproducing organisms is a mechanism to merge gamete genomes and, in multicellular organisms, it is a strategy to sculpt organs, such as muscle, bone, and placenta. Moreover, this mechanism has been implicated in pathological conditions, such as infection and cancer.
Aguilar +15 more
openaire +3 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
The bone-resorbing activity of osteoclasts plays a critical role in the life-long remodeling of our bones that is perturbed in many bone loss diseases. Multinucleated osteoclasts are formed by the fusion of precursor cells, and larger cells – generated ...
Evgenia Leikina +5 more
doaj +1 more source
Aging-dependent functional alterations of mitochondrial DNA (mtDNA) from human fibroblasts transferred into mtDNA-less cells [PDF]
To investigate the role that aging-dependent accumulation of mitochondrial DNA (mtDNA) mutations plays in the senescence processes, mitochondria from fibroblasts of 21 normal human individuals between 20 weeks (fetal) and 103 years of age were introduced
Attardi, Giuseppe +5 more
core +1 more source
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source
TAGLN2-Regulated Trophoblast Migration, Invasion and Fusion are Impaired in Preeclampsia
Preeclampsia (PE) is a serious disease during pregnancy that affects approximately eight million mothers and infants worldwide each year and is closely related to abnormal trophoblast function.
Hao Wang +10 more
doaj +1 more source

