Results 61 to 70 of about 12,374,157 (394)

Myeloid cell‐derived tumor necrosis factor‐alpha promotes sarcopenia and regulates muscle cell fusion with aging muscle fibers

Aging Cell, 2018
Sarcopenia is age‐related muscle wasting that lacks effective therapeutic interventions. We found that systemic ablation of tumor necrosis factor‐α (TNF‐α) prevented sarcopenia and prevented age‐related change in muscle fiber phenotype.
Ying Wang, Steven S. Welc, Michelle Wehling-Henricks, J. Tidball   +3 more
semanticscholar   +1 more source

Methylation Pathways and SARS-CoV-2 Lung Infiltration and Cell Membrane-Virus Fusion Are Both Subject to Epigenetics

Frontiers in Cellular and Infection Microbiology, 2020
The recent pandemic SARS-CoV-2 outbreak affects all kinds of individuals worldwide. The health, social, and economic impacts of the pandemic are dramatic, and vaccines or specific treatment options are not yet available.
Leo Pruimboom, Leo Pruimboom
doaj   +1 more source

Atypically Shaped Cardiomyocytes (ACMs): The Identification, Characterization and New Insights into a Subpopulation of Cardiomyocytes

Biomolecules, 2022
In the adult mammalian heart, no data have yet shown the existence of cardiomyocyte-differentiable stem cells that can be used to practically repair the injured myocardium.
Mariko Omatsu-Kanbe, Ryo Fukunaga, Xinya Mi, Hiroshi Matsuura   +3 more
doaj   +1 more source

V-fusion: a convenient, nontoxic method for cell fusion

BioTechniques, 2010
Cell-to-cell fusion (cell fusion) is a fundamental biological process that also has been used as a versatile experimental tool to dissect a variety of cellular mechanisms, including the consequences of cell fusion itself, and to produce cells with ...
Amy Gottesman, Joseph Milazzo, Yuri Lazebnik   +2 more
doaj   +1 more source

A Cellular Assay for Spike/ACE2 Fusion: Quantification of Fusion-Inhibitory Antibodies after COVID-19 and Vaccination

Viruses, 2022
Not all antibodies against SARS-CoV-2 inhibit viral entry, and hence, infection. Neutralizing antibodies are more likely to reflect real immunity; however, certain tests investigate protein/protein interaction rather than the fusion event.
Fabien Abdul, Pascale Ribaux, Aurélie Caillon, Astrid Malézieux-Picard, Virginie Prendki, Nathalie Vernaz, Nikolay Zhukovsky, Flavien Delhaes, Karl-Heinz Krause, Olivier Preynat-Seauve   +9 more
doaj   +1 more source

The microprotein Minion controls cell fusion and muscle formation

Nature Communications, 2017
Although recent evidence has pointed to the existence of small open reading frame (smORF)-encoded microproteins in mammals, their function remains to be determined.
Qiao-Hua Zhang, A. Vashisht, J. O’Rourke, S. Corbel, Rita Moran, Angelica Romero, L. Miraglia, Jia Zhang, Eric Durrant, C. Schmedt, S. Sampath, Srihari C. Sampath   +11 more
semanticscholar   +1 more source

Human Myoblast and Mesenchymal Stem Cell Interactions Visualized by Videomicroscopy. [PDF]

, 2015
Muscle-derived progenitor cell (myoblast) therapy has promise for the treatment of denervated, weakened, and fibrotic muscle. The best methods for injecting myoblasts to promote fusion and retention have yet to be determined, however.
Belafsky, Peter C, Black, Amanda B, Dahlenburg, Heather, Kuhn, Maggie A, Nacey, Catherine, Nolta, Jan A, Pepper, Karen, Pontow, Suzanne   +7 more
core   +1 more source

Genetic basis of cell-cell fusion mechanisms. [PDF]

Trends in Genetics, 2013
Cell-cell fusion in sexually reproducing organisms is a mechanism to merge gamete genomes and, in multicellular organisms, it is a strategy to sculpt organs, such as muscle, bone, and placenta. Moreover, this mechanism has been implicated in pathological conditions, such as infection and cancer.
P. Aguilar, M. Baylies, A. Fleissner, L. Helming, Naokazu Inoue, B. Podbilewicz, Hongmei Wang, M. Wong   +7 more
semanticscholar   +4 more sources

FOntCell: Fusion of Ontologies of Cells [PDF]

Frontiers in Cell and Developmental Biology, 2019
High-throughput cell-data technologies such as single-cell RNA-seq create a demand for algorithms for automatic cell classification and characterization. There exist several cell classification ontologies with complementary information. However, one needs to merge them to synergistically combine their information.
Javier Cabau-Laporta, Alex M. Ascensión, Mikel Arrospide-Elgarresta, Daniela Gerovska, Daniela Gerovska, Marcos J. Araúzo-Bravo, Marcos J. Araúzo-Bravo, Marcos J. Araúzo-Bravo, Marcos J. Araúzo-Bravo, Marcos J. Araúzo-Bravo, Marcos J. Araúzo-Bravo   +10 more
openaire   +6 more sources

Formation of multinucleated osteoclasts depends on an oxidized species of cell surface-associated La protein

eLife
The bone-resorbing activity of osteoclasts plays a critical role in the life-long remodeling of our bones that is perturbed in many bone loss diseases. Multinucleated osteoclasts are formed by the fusion of precursor cells, and larger cells – generated ...
Evgenia Leikina, Jarred M Whitlock, Kamran Melikov, Wendy Zhang, Michael P Bachmann, Leonid Chernomordik   +5 more
doaj   +1 more source