Results 61 to 70 of about 755,884 (339)

The Dark Side of Cell Fusion [PDF]

open access: yesInternational Journal of Molecular Sciences, 2016
Cell fusion is a physiological cellular process essential for fertilization, viral entry, muscle differentiation and placental development, among others. In this review, we will highlight the different cancer cell-cell fusions and the advantages obtained by these fusions. We will specially focus on the acquisition of metastatic features by cancer cells
Bastida Ruiz, Daniel   +2 more
openaire   +3 more sources

An Attempt at Fusing Primordial Germ Cell with Embryonic Blood Cell in Chickens Using Inactivated Sendai Virus or Electrical Stimulation

open access: yesThe Journal of Poultry Science, 2005
In order to produce nuclear transferred PGCs, fusion of primordial germ cell (PGC) with embryonic blood cell (EBC) was attempted. PGCs and EBCs were isolated from the blood of stages 13-15 embryos.
Mitsuru Naito   +3 more
doaj   +1 more source

Unilateral Cleavage Furrows in Multinucleate Cells

open access: yesCells, 2020
Multinucleate cells can be produced in Dictyostelium by electric pulse-induced fusion. In these cells, unilateral cleavage furrows are formed at spaces between areas that are controlled by aster microtubules.
Julia Bindl   +5 more
doaj   +1 more source

Quantifying the Sensitivity of HIV-1 Viral Entry to Receptor and Coreceptor Expression [PDF]

open access: yesJ. Phys. Chem. B, 2016, 120 (26), pp 6189-6199, 2018
Infection by many viruses begins with fusion of viral and cellular lipid membranes, followed by entry of viral contents into the target cell and ultimately, after many biochemical steps, integration of viral DNA into that of the host cell. The early steps of membrane fusion and viral capsid entry are mediated by adsorption to the cell surface, and ...
arxiv   +1 more source

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

open access: yesFEBS Letters, EarlyView.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley   +2 more
wiley   +1 more source

Cell fusion in the liver, revisited [PDF]

open access: yesWorld Journal of Hepatology, 2018
There is wide agreement that cell fusion is a physiological process in cells in mammalian bone, muscle and placenta. In other organs, such as the cerebellum, cell fusion is controversial. The liver contains a considerable number of polyploid cells: They are commonly believed to originate by genome endoreplication, although the contribution of cell ...
Lizier Michela   +5 more
openaire   +4 more sources

The Neoplasia as embryological phenomenon and its implication in the animal evolution and the origin of cancer. III. The role of flagellated cell fusion in the formation of the first animal and evolutionary clues to the Warburg effect [PDF]

open access: yesarXiv, 2022
Cytasters have been underestimated in terms of their potential relevance to embryonic development and evolution. From the perspective discussed herein, structures such as the multiciliated cells of comb rows and balancers supporting mineralized statoliths and macrocilia in Beroe ovata point to a past event of multiflagellate fusion in the origin of ...
arxiv  

Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase

open access: yesFEBS Letters, EarlyView.
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri   +8 more
wiley   +1 more source

HIV-1 Fusion with CD4+ T cells Is Promoted by Proteins Involved in Endocytosis and Intracellular Membrane Trafficking

open access: yesViruses, 2019
The HIV-1 entry pathway into permissive cells has been a subject of debate. Accumulating evidence, including our previous single virus tracking results, suggests that HIV-1 can enter different cell types via endocytosis and CD4/coreceptor-dependent ...
Mariana Marin   +4 more
doaj   +1 more source

Multiple stalk formation as a pathway of defect-induced membrane fusion [PDF]

open access: yes, 2004
We propose that the first stage of membrane fusion need not be the formation of a single stalk. Instead, we consider a scenario for defect-induced membrane fusion that proceeds cooperatively via multiple stalk formation. The defects (stalks or pores) attract each other via membrane-mediated capillary interactions that result in a condensation ...
arxiv   +1 more source

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