Results 61 to 70 of about 5,651,556 (349)

Symbiotic Cell Differentiation and Cooperative Growth in Multicellular Aggregates

, 2016
As cells grow and divide under a given environment, they become crowded and resources are limited, as seen in bacterial biofilms and multicellular aggregates.
Kaneko, Kunihiko, Saito, Nen, Yamagishi, Jumpei F   +2 more
core   +2 more sources

Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism [PDF]

, 2012
Cancer cells must satisfy the metabolic demands of rapid cell growth within a continually changing microenvironment. We demonstrated that the dynamic posttranslational modification of proteins by O-linked β-N-acetylglucosamine (O-GlcNAcylation) is a key ...
Clark, Peter M., Driggers, Edward M., Goddard, William A., III, Hill, Collin, Hsieh-Wilson, Linda C., Keenan, Marie C., Mason, Daniel E., Peters, Eric C., Yi, Wen   +8 more
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

BMP2 is Superior to BMP4 for Promoting Human Muscle-Derived Stem Cell-Mediated Bone Regeneration in a Critical-Sized Calvarial Defect Model

Cell Transplantation, 2013
Muscle-derived cells have been successfully isolated using a variety of different methods and have been shown to possess multilineage differentiation capacities, including an ability to differentiate into articular cartilage and bone in vivo; however ...
Xueqin Gao, Arvydas Usas, Aiping Lu, Ying Tang, Bing Wang, Chien-Wen Chen, Hongshuai Li, Jessica C. Tebbets, James H. Cummins, Johnny Huard   +9 more
doaj   +1 more source

Universal relationship in gene-expression changes for cells in steady-growth state

, 2014
Cells adapt to different conditions by altering a vast number of components, which is measurable using transcriptome analysis. Given that a cell undergoing steady growth is constrained to sustain each of its internal components, the abundance of all the ...
Furusawa, Chikara, Kaneko, Kunihiko, Yomo, Tetsuya   +2 more
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Deterministic and stochastic descriptions of gene expression dynamics

, 2012
A key goal of systems biology is the predictive mathematical description of gene regulatory circuits. Different approaches are used such as deterministic and stochastic models, models that describe cell growth and division explicitly or implicitly etc ...
A.M. Walczak, C. Tan, C.V. Rao, D.L. Cook, David Gomez, E. Andrianantoandro, E.M. Ozbudak, H. Bremer, H.H. McAdams, I. Golding, J. Hasty, J. Hasty, J. Paulsson, J. Paulsson, J. Peccoud, J. Yu, J.A. Bernstein, J.L. Spudich, K. Nath, L. Bintu, L. Cai, M. Kaern, M. Scott, M. Scott, M. Thattai, M.B. Elowitz, M.E. Csete, M.E. Wall, M.S. Ko, N. Brenner, N. Mitarai, N.A. Cookson, N.J. Guido, O.G. Berg, O.G. Berg, P. Guptasarma, P. Wang, P.S. Swain, R. Kwok, Rahul Marathe, S. Cooper, S. Cooper, S. Klumpp, S. Klumpp, S. Klumpp, S. Klumpp, S. Klumpp, S. Reeh, Stefan Klumpp, U. Alon, Veronika Bierbaum, Y. Taniguchi   +51 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

An In Vitro Human Liver Model by iPSC-Derived Parenchymal and Non-parenchymal Cells

Stem Cell Reports, 2017
Summary: During liver development, hepatoblasts and liver non-parenchymal cells (NPCs) such as liver sinusoidal endothelial cells (LSECs) and hepatic stellate cells (HSCs) constitute the liver bud where they proliferate and differentiate. Accordingly, we
Yuta Koui, Taketomo Kido, Toshimasa Ito, Hiroki Oyama, Shin-Wei Chen, Yuki Katou, Katsuhiko Shirahige, Atsushi Miyajima   +7 more
doaj   +1 more source

The Living Fossil Psilotum nudum Has Cortical Fibers With Mannan-Based Cell Wall Matrix

Frontiers in Plant Science, 2020
Cell wall thickening and development of secondary cell walls was a major step in plant terrestrialization that provided the mechanical support, effective functioning of water-conducting elements and fortification of the surface tissues.
Tatyana Chernova, Marina Ageeva, Polina Mikshina, Oksana Trofimova, Liudmila Kozlova, Simcha Lev-Yadun, Tatyana Gorshkova   +6 more
doaj   +1 more source