Phosphodiesterase BpdE suppress bacterial proliferation by regulating <i>min</i> operon in <i>Brucella abortus</i>. [PDF]
Chen J +7 more
europepmc +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Non-transport functions of motor proteins in corticogenesis. [PDF]
Mitina N +3 more
europepmc +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
A predictive model for coupling cell division orientation to tissue mechanics during epithelial morphogenesis. [PDF]
Azote S, Negi RS, Chen NA, Manning ML.
europepmc +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Onset and Seasonal Kinetics of Xylogenesis in <i>Pinus sylvestris</i> L. on the Southern Fringes of Its Distribution Depend on Early Spring Air and Soil Temperature. [PDF]
Belokopytova LV +6 more
europepmc +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Dynamics of Functional Traits and Molecular Regulation in the Vascular Cambium Across Different Ages of <i>Styphnolobium japonicum</i>. [PDF]
Gao X +11 more
europepmc +1 more source
Contributions of intra- and extracellular antibiotic degradation to collective [Formula: see text]-lactam survival. [PDF]
Gross R +7 more
europepmc +1 more source

