Results 31 to 40 of about 11,162,346 (238)

Targeted transgenic RNAi knockdown of cell fate determinants induces neoplastic tumor growth and metastasis in a Drosophila transplantation model of neural stem cell derived cancer [PDF]

, 2012
Genetic models such as Drosophila have sophisticated transgenic and molecular genetic tools available to investigate proliferation control in normal and tumorigenic neural stem cells.
Reichert, Heinrich, Laurenson, Anne-Sophie, Saini, Nidhi, Jiang, Yanrui   +3 more
core   +1 more source

Stochastic modeling for a better approach of the in vitro observed growth of colon adenocarcinoma cells

Brazilian Archives of Biology and Technology, 2006
The definition of a stochastic model that reflects the cell growth and the use of computer software could be very useful in modelling the cell behaviour due to the possibility to introduce alterations in biology parameters to obtain different growth ...
Miguel J. Ruiz-Gómez, Antonio Ruiz-Gómez, Manuel Martínez Morillo   +2 more
doaj   +1 more source

A Conserved Cell Growth Cycle Can Account for the Environmental Stress Responses of Divergent Eukaryotes [PDF]

, 2012
The respiratory metabolic cycle in budding yeast (Saccharomyces cerevisiae) consists of two phases most simply defined phenomenologically: low oxygen consumption (LOC) and high oxygen consumption (HOC).
Airoldi, Edoardo|, Airoldi, E.M., Airoldi, EM, Airoldi, Edoardo M, Botstein, D., van Oudenaarden, Alexander, Airoldi, Edoardo, Van Oudenaarden, A, Botstein, David, Slavov, Nikolai G, Botstein, D, Slavov, N., Airoldi, Edoardo M., Slavov, N, van Oudenaarden, A., Slavov, Nikolai   +15 more
core   +1 more source

Artificial thymic organoid culture generates functional iPSC-derived CD4+ invariant natural killer T cells

Communications Biology
Invariant NKT (iNKT) cells have a T-cell receptor that is common to all individuals and are activated by recognizing glycolipids on MHC class I-like CD1d molecules.
Sara Shiina, Tatsuki Ueda, Shoichi Iriguchi, Yasushi Uemura, Shin Kaneko   +4 more
doaj   +1 more source

Bridging the Timescales of Single-Cell and Population Dynamics

Physical Review X, 2018
How are granular details of stochastic growth and division of individual cells reflected in smooth deterministic growth of population numbers? We provide an integrated, multiscale perspective of microbial growth dynamics by formulating a data-validated ...
Farshid Jafarpour, Charles S. Wright, Herman Gudjonson, Jedidiah Riebling, Emma Dawson, Klevin Lo, Aretha Fiebig, Sean Crosson, Aaron R. Dinner, Srividya Iyer-Biswas   +9 more
doaj   +1 more source

Generation of HIV-Resistant Macrophages from IPSCs by Using Transcriptional Gene Silencing and Promoter-Targeted RNA

Molecular Therapy: Nucleic Acids, 2018
Highly active antiretroviral therapy (HAART) has markedly prolonged the prognosis of HIV-1 patients. However, lifelong dependency on HAART is a continuing challenge, and an effective therapeutic is much desired.
Kei Higaki, Masako Hirao, Ai Kawana-Tachikawa, Shoichi Iriguchi, Ayako Kumagai, Norihiro Ueda, Wang Bo, Sanae Kamibayashi, Akira Watanabe, Hiromitsu Nakauchi, Kazuo Suzuki, Shin Kaneko   +11 more
doaj   +1 more source

Nutrient sensing kinases PKA and Sch9 phosphorylate the catalytic domain of the ubiquitin-conjugating enzyme Cdc34. [PDF]

PLoS ONE, 2011
Cell division is controlled in part by the timely activation of the CDK, Cdc28, through its association with G1 and G2 cyclins. Cdc28 complexes are regulated in turn by the ubiquitin conjugating enzyme Cdc34 and SCF ubiquitin ligase complexes of the ...
Ross Cocklin, Mark Goebl
doaj   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Reduced expression of the SHORT-ROOT gene increases the rates of growth and development in hybrid Poplar and Arabidosis [PDF]

, 2011
SHORT-ROOT (SHR) is a well characterized regulator of cell division and cell fate determination in the Arabidopsis primary root. However, much less is known about the functions of SHR in the aerial parts of the plant.
Brian Jones, Mellerowicz, Ewa J., Gaboreanu, Ioana, Sandberg, Göran,, Wang, J., Jones Brian, Hertzberg, M., Magnus Hertzberg, Andersson-Gunnerås Sara, Sandberg, Göran, Göran Sandberg, Zheng, B., Mellerowicz, Ewa, Andersson-Gunneras, S., Laux, T., Jones, B., Sara Andersson-Gunnerås, Wang, Jiehua, Matthew R. Tucker, Gaboreanu, I., Tucker Matthew R., Mellerowicz Ewa J., Hertzberg, Magnus, Thomas Laux, Zheng, Bo,, Lesniewska, Joanna, Gaboreanu Ioana, Ewa J. Mellerowicz, Jones, Brian, Ioana Gaboreanu, Tucker, M., Sandberg, G., Gaboreanu, Ioana,, Lesniewska, J., Laux Thomas, Jiehua Wang, Ewa J Mellerowicz, Mellerowicz, E., Laux, Thomas, Leśniewska Joanna, Sandberg Göran, Zheng, Bo, Jones, Brian,, Matthew R Tucker, Hertzberg Magnus, Andersson-Gunneras, Sara, Wang, Jiehua,, Gunnerås, Sara, Tucker, Matthew R., Zheng Bo, Joanna Leśniewska, Wang Jiehua, Bo Zheng   +52 more
core   +2 more sources

TRPV4‐mediated Ca2+ deregulation causes mitochondrial dysfunction via the AKT/α‐synuclein pathway in dopaminergic neurons

FASEB BioAdvances, 2023
Mutations in the gene encoding the transient receptor potential vanilloid member 4 (TRPV4), a Ca2+ permeable nonselective cation channel, cause TRPV4‐related disorders.
Xiao Sun, Jun Kong, Shuangshan Dong, Hiroki Kato, Hiroshi Sato, Yuta Hirofuji, Yosuke Ito, Lu Wang, Takahiro A. Kato, Michiko Torio, Yasunari Sakai, Shouichi Ohga, Satoshi Fukumoto, Keiji Masuda   +13 more
doaj   +1 more source