Results 101 to 110 of about 599,693 (212)
Hypoxia Decreases Mitochondrial ROS Production in Cells
Free Radical Biology and MedicineWe re-examined the reported increase in mitochondrial ROS production during acute hypoxia in cells. Using the Amplex Ultrared/horseradish peroxidase assay we found a decrease, not increase, in hydrogen peroxide release from HEK293 cells under acute hypoxia, at times ranging from 1 min to 3 h.
Bijoya Sen +2 more
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Radiation and chemotherapy variable response induced by tumor cell hypoxia: impact of radiation dose, anticancer drug, and type of cancer. [PDF]
Radiat Environ Biophys, 2022 Ibrahim AM +3 more
europepmc +1 more source
Generalizable synthesis of bioresponsive near-infrared fluorescent probes: sulfonated heptamethine cyanine prototype for imaging cell hypoxia. [PDF]
Org Biomol Chem, 2021 Atkinson KM +3 more
europepmc +1 more source
11LBA Cell reprogramming by hypoxia
European Journal of Cancer Supplements, 2009 Background: Low oxygen tension (hypoxia) is an important determinant in tumor progression. In this study we assess the prognostic value of an in vitro derived hypoxia gene signature in neuroblastoma patients. Material and Methods: L1-L2 regularization framework has been applied on gene expression profiles of 11 neuroblastoma cell lines to define the ...
L. Varesio +5 more
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Redox signaling during hypoxia in mammalian cells
Redox Biology, 2017 Hypoxia triggers a wide range of protective responses in mammalian cells, which are mediated through transcriptional and post-translational mechanisms. Redox signaling in cells by reactive oxygen species (ROS) such as hydrogen peroxide (H2O2) occurs through the reversible oxidation of cysteine thiol groups, resulting in structural modifications that ...
Kimberly A. Smith +2 more
openaire +3 more sources
Cardiology Research and Practice, 2019 Objective. MiR-133b was dysregulated in myocardial infarction. However, the role and mechanism of miR-133b in myocardial infarction remains unclear.
Yongmei Zhou, Hui Huang, Xiaolin Hou
doaj +1 more source
Artificial Cells, Nanomedicine, and Biotechnology, 2019 Background Myocardial ischemia is the main reason for ischemic heart disease. Baicalin is a plant-derived flavonoid with cardio-protective activity.
Hailiang Yu, Bin Chen, Qi Ren
doaj +1 more source
iScienceSummary: Cancer cells in solid tumors experience hypoxia, a condition of low O2 concentration, since their O2 demand exceeds the supply from the surrounding vasculature. However, how these cells adapt to hypoxia requires further elucidation. Here, we use
Noreen Hosny +14 more
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In the eye of the storm: T cell behavior in the inflammatory microenvironment. [PDF]
, 2013 Coordinated unfolding of innate and adaptive immunity is key to the development of protective immune responses. This functional integration occurs within the inflamed tissue, a microenvironment enriched with factors released by innate and subsequently ...
Haas, R, Marelli-Berg, F, Mauro, C
core +1 more source
Scientific Reports, 2018 Hypoxia is a common feature of solid tumours that promotes invasion and metastatic dissemination. Invadopodia are actin-rich membrane protrusions that direct extracellular matrix proteolysis and facilitate tumour cell invasion.
Céline Hoffmann +10 more
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