Results 111 to 120 of about 599,693 (212)
BMC NeurologyBackground Stroke is a cerebrovascular disease that is the main cause of death and disability worldwide. Hypoxia is a major factor that causes neuronal damage and even cellular death.
Yamei Wang +11 more
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Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension. [PDF]
, 2018 Concentric lung vascular wall thickening due to enhanced proliferation of pulmonary arterial smooth muscle cells is an important pathological cause for the elevated pulmonary vascular resistance reported in patients with pulmonary arterial hypertension ...
Ayon, Ramon J +18 more
core +1 more source
Widespread depolarization during expiration: A source of respiratory drive? [PDF]
, 2014 Respiration influences various pacemakers and rhythms of the body during inspiration and expiration but the underlying mechanisms are relatively unknown.
Barnes, Vernon A. +3 more
core
Molecular responses to hypoxia in tumor cells.
Molecular cancer, 2003 Highly aggressive, rapidly growing tumors are exposed to hypoxia or even anoxia which occurs as a consequence of inadequate blood supply. Both hypoxia and consecutive hypoxia/reoxygenation exert a variety of influences on tumor cell biology. Among these are activation of certain signal transduction pathways and gene regulatory mechanisms, induction of ...
Ibrahim Saleh M, Kunz Manfred
openaire +3 more sources
Hypoxia-induced HIF-1α/VASN promotes bladder cancer progression
Scientific ReportsHypoxia-inducible factor-1 α (HIF-1α) is important in regulating the hypoxia adaptive response of bladder cancer. Vasorin (VASN) is closely related to tumor development. However, the role of VASN in hypoxia-induced bladder cancer remains to be clarified.
Qian-jin Zhang +8 more
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Mesenchymal stem cell‑derived extracellular vesicles prevent neural stem cell hypoxia injury via promoting miR‑210‑3p expression. [PDF]
Mol Med Rep, 2020 Li F +6 more
europepmc +1 more source
Effects of Hyperbaric Hypoxia on Some Enzyme Systems in the Mammalian Liver [PDF]
, 1978 The metabolic effects of hypobaric hypoxic stress on the mammalian liver were studied. The lactate dehydrogenase (LDH) and succinate dehydrogenase (SDH) activity of mouse liver homogenates were measured after exposure to an equivalent altitude of 36,000 ...
Baeyens, Dennis A., Meier, M. J.
core +2 more sources
CD44ICD promotes breast cancer stemness via PFKFB4-mediated glucose metabolism. [PDF]
, 2018 CD44 is a single-pass cell surface glycoprotein that is distinguished as the first molecule used to identify cancer stem cells in solid tumors based on its expression.
Gao, Ruifang +11 more
core
Hypoxia Induced Downregulation of Na+/H+ Exchanger-1 Activity Decreases Tumor Cell Proliferation
Ankara Üniversitesi Tıp Fakültesi MecmuasıObjectives: Hypoxia and acidosis are the hallmarks of proliferative tumor microenvironment which can modulate the expression and function of Na+/H+ exchanger-1 (NHE1) via hypoxia inducible factor 1 (Hif).
Gül Şimşek, Hilmi Burak Kandilci
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