Results 21 to 30 of about 619,300 (360)

Plasma from Volunteers Breathing Helium Reduces Hypoxia-Induced Cell Damage in Human Endothelial Cells-Mechanisms of Remote Protection Against Hypoxia by Helium. [PDF]

open access: yes, 2019
PurposeRemote ischemic preconditioning protects peripheral organs against prolonged ischemia/reperfusion injury via circulating protective factors. Preconditioning with helium protected healthy volunteers against postischemic endothelial dysfunction.
Augustijn, Quinten JJ   +7 more
core   +1 more source

One special question to start with: can HIF/NFkB be a target in inflammation? [PDF]

open access: yes, 2015
Hypoxia and Inflammation are strictly interconnected with important consequences at clinical and therapeutic level. While cell and tissue damage due to acute hypoxia mostly leads to cell necrosis, in chronic hypoxia, cells that are located closer to ...
CARNEVALE, ILARIA   +8 more
core   +1 more source

Avaliação dos níveis séricos de testosterona em pacientes com síndrome da apneia obstrutiva do sono Evaluation of testosterone serum levels in patients with obstructive sleep apnea syndrome

open access: yesBrazilian Journal of Otorhinolaryngology, 2011
Homens com síndrome da apneia obstrutiva do sono (SAOS) podem apresentar diminuição dos níveis de testosterona devido à hipóxia. OBJETIVOS: Relacionar os níveis séricos da testosterona, em pacientes com SAOS, com parâmetros clínico-laboratoriais ...
Fernando Drimel Molina   +6 more
doaj   +1 more source

Platelet-rich plasma pretreatment protects anterior cruciate ligament fibroblasts correlated with PI3K-Akt-mTOR pathway under hypoxia condition

open access: yesJournal of Orthopaedic Translation, 2022
Background: /Objective: Biological factors such as platelet-rich plasma (PRP) combined with anterior cruciate ligament (ACL) primary repair technology are used to treat ACL injury.
Yanwei Cao   +6 more
doaj   +1 more source

Ferroptosis Regulated by Hypoxia in Cells

open access: yesCells, 2023
Ferroptosis is an oxidative damage-related, iron-dependent regulated cell death with intracellular lipid peroxide accumulation, which is associated with many physiological and pathological processes. It exhibits unique features that are morphologically, biochemically, and immunologically distinct from other regulated cell death forms.
Xiangnan Zheng, Yuqiong Liang, Cen Zhang
openaire   +3 more sources

Activación de STAT3 por hipoxia en modelos in vitro de cáncer de cuello uterino y en células endoteliales

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2017
Introducción. El microambiente tumoral influye en el comportamiento de las células cancerosas. Especialmente, el estímulo de agentes estresantes, como la hipoxia, se convierte en un factor crítico para la evolución y el tratamiento del cáncer.
Óscar Ortega   +2 more
doaj   +1 more source

Cell line development for continuous high cell density biomanufacturing: Exploiting hypoxia for improved productivity

open access: yesMetabolic Engineering Communications, 2021
Oxygen deficiency (hypoxia) induces adverse effects during biotherapeutic protein production leading to reduced productivity and cell growth. Hypoxic conditions occur during classical batch fermentations using high cell densities or perfusion processes ...
Nikolas Zeh   +5 more
doaj   +1 more source

Hypoxia, stem cells and bone tumor [PDF]

open access: yesCancer Letters, 2011
Normal oxygen level is critical for niches that together with other components of the niche play vital role in regulating stem or tumor cells behavior. Hypoxia plays an important role in normal development and disease progression, including the growth of solid tumors.
Wen, Zeng   +4 more
openaire   +2 more sources

Vascular changes in the rat brain during chronic hypoxia in the presence and absence of hypercapnia. [PDF]

open access: yes, 2005
Changes in brain vascularity in adult rats during adaptation to chronic normobaric hypoxia with or without elevated CO(2) were morphometrically investigated.
Hayashida, Yoshiaki   +6 more
core   +1 more source

Divergent mutational processes distinguish hypoxic and normoxic tumours. [PDF]

open access: yes, 2020
Many primary tumours have low levels of molecular oxygen (hypoxia), and hypoxic tumours respond poorly to therapy. Pan-cancer molecular hallmarks of tumour hypoxia remain poorly understood, with limited comprehension of its associations with specific ...
Bhandari, Vinayak   +4 more
core   +1 more source

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