Results 31 to 40 of about 11,093,569 (425)
Hypoxia Signaling Pathway in Stem Cell Regulation: Good and Evil [PDF]
, 2018 Purpose of Review: This review summarizes the role of hypoxia and hypoxia-inducible factors (HIFs) in the regulation of stem cell biology, specifically focusing on maintenance, differentiation, and stress responses in the context of several stem cell ...
Aljoufi, Arafat +3 more
core +1 more source
Stem cell research & therapeutics, 2020 Hypoxia is a major cause of beta cell death and dysfunction after transplantation. The aim of this study was to investigate the effect of exosomes derived from mesenchymal stem cells (MSCs) on beta cells under hypoxic conditions and the potential ...
Jin Chen +13 more
semanticscholar +1 more source
Experimental Cell Research, 2017 The ability of cells to sense and adapt to changes in oxygen is mediated by hypoxia-inducible factor (HIF). Immune cells function in physiologically complex and varying environments whereby oxygen, pH, nutrients, metabolites and cytokines are continuously fluctuating.
Burrows, N, Maxwell, PH
openaire +4 more sources
Brazilian Journal of Otorhinolaryngology, 2011 Homens com síndrome da apneia obstrutiva do sono (SAOS) podem apresentar diminuição dos níveis de testosterona devido à hipóxia. OBJETIVOS: Relacionar os níveis séricos da testosterona, em pacientes com SAOS, com parâmetros clínico-laboratoriais ...
Fernando Drimel Molina +6 more
doaj +1 more source
Defining the role of oxygen tension in human neural progenitor fate. [PDF]
, 2014 Hypoxia augments human embryonic stem cell (hESC) self-renewal via hypoxia-inducible factor 2α-activated OCT4 transcription. Hypoxia also increases the efficiency of reprogramming differentiated cells to a pluripotent-like state. Combined, these findings
Cinkornpumin, Jessica +10 more
core +1 more source
Frontiers in Bioscience-Landmark, 2021 Objective: Nucleus pulposus cells (NPCs) are cells extracted from the intervertebral disc and are important for research into intervertebral disc degeneration (IVDD). NPCs live in an avascular and relatively hypoxic environment.
Xiao-Xin Gao +8 more
doaj +1 more source
Optical and magnetic resonance imaging approaches for investigating the tumour microenvironment: state-of-the-art review and future trends [PDF]
Nanotechnology, Volume 32, Number 6, 062001, 2021, 2021 The tumour microenvironment (TME) strongly influences tumorigenesis and metastasis. Two of the most characterized properties of the TME are acidosis and hypoxia, both of which are considered hallmarks of tumours as well as critical factors in response to anticancer treatments.
arxiv +1 more source
Biomédica: revista del Instituto Nacional de Salud, 2017 Introducción. El microambiente tumoral influye en el comportamiento de las células cancerosas. Especialmente, el estímulo de agentes estresantes, como la hipoxia, se convierte en un factor crítico para la evolución y el tratamiento del cáncer.
Óscar Ortega +2 more
doaj +1 more source
One special question to start with: can HIF/NFkB be a target in inflammation? [PDF]
, 2015 Hypoxia and Inflammation are strictly interconnected with important consequences at clinical and therapeutic level. While cell and tissue damage due to acute hypoxia mostly leads to cell necrosis, in chronic hypoxia, cells that are located closer to ...
CARNEVALE, ILARIA +8 more
core +1 more source
NK cells, hypoxia and trophoblast cell differentiation [PDF]
Cell Cycle, 2012 Hemochorial placentation is characterized by extensive remodeling of the maternal vasculature, converting them to flaccid low resistance vessels. This process greatly facilitates exchange of nutrients and gases between the mother and the fetus. Two key modulators that orchestrate these vascular changes have been identified at the maternal fetal ...
Damayanti Chakraborty +2 more
openaire +2 more sources