Results 1 to 10 of about 3,688,452 (227)

Early IgE Production Is Linked with Extrafollicular B- and T-Cell Activation in Low-Dose Allergy Model

open access: yesVaccines, 2022
Despite its paramount importance, the predominant association of early IgE production with harmless antigens, via germinal-center B- and T-cell subpopulations or extrafollicular activation, remains unresolved.
Dmitrii Borisovich Chudakov   +6 more
doaj   +1 more source

3D Organoids for Regenerative Endodontics

open access: yesBiomolecules, 2023
Apical periodontitis is the inflammation and destruction of periradicular tissues, mediated by microbial factors originating from the infected pulp space. This bacteria-mediated inflammatory disease is known to interfere with root development in immature
Fang-Chi Li, Anil Kishen
doaj   +1 more source

Cell–Biomaterial Interactions

open access: yesBioengineering, 2023
In animals, the extracellular matrix (ECM) forms a three-dimensional network occupying the intercellular spaces (interstitial matrix) or serving as physical and biochemical support for cells and tissues (basement membrane) [...]
Vincent Deplaigne, Gael Y. Rochefort
openaire   +3 more sources

Defining the role of neutrophils in the lung during infection: Implications for tuberculosis disease

open access: yesFrontiers in Immunology, 2022
Neutrophils are implicated in the pathogenesis of many diseases involving inflammation. Neutrophils are also critical to host defence and have a key role in the innate immune response to infection.
E. Gaffney   +6 more
doaj   +1 more source

Heterogeneity of glioblastoma stem cells in the context of the immune microenvironment and geospatial organization

open access: yesFrontiers in Oncology, 2022
Glioblastoma (GBM) is an extremely aggressive and incurable primary brain tumor with a 10-year survival of just 0.71%. Cancer stem cells (CSCs) are thought to seed GBM’s inevitable recurrence by evading standard of care treatment, which combines surgical
Aryeh Silver   +10 more
doaj   +1 more source

Advances in Non-Chemical Tools to Control Poultry Hematophagous Mites

open access: yesVeterinary Sciences, 2023
The blood-sucking mites Dermanyssus gallinae (“red mite”), Ornithonyssus sylviarum (“northern fowl mite”), and Ornithonyssus bursa (”tropical fowl mite”) stand out for causing infestations in commercial poultry farms worldwide, resulting in significant ...
Geralda Gabriele da Silva   +12 more
doaj   +1 more source

T-Cell Subpopulations Exhibit Distinct Recruitment Potential, Immunoregulatory Profile and Functional Characteristics in Chagas versus Idiopathic Dilated Cardiomyopathies

open access: yesFrontiers in Cardiovascular Medicine, 2022
Chronic Chagas cardiomyopathy (CCC) is one of the deadliest cardiomyopathies known and the most severe manifestation of Chagas disease, which is caused by infection with the parasite Trypanosoma cruzi.
Eula G. A. Neves   +18 more
doaj   +1 more source

Transmission-Blocking Vaccines for Canine Visceral Leishmaniasis: New Progress and Yet New Challenges

open access: yesVaccines, 2023
Dogs with visceral leishmaniasis play a key role in the transmission cycle of Leishmania infantum to humans in the urban environment. There is a consensus regarding the importance of developing a vaccine to control this disease.
Jaqueline Costa Leite   +19 more
doaj   +1 more source

Multiscale modelling of cancer progression and treatment control : the role of intracellular heterogeneities in chemotherapy treatment [PDF]

open access: yes, 2015
Cancer is a complex, multiscale process involving interactions at intracellular, intercellular and tissue scales that are in turn susceptible to microenvironmental changes.
Chaplain, Mark Andrew Joseph   +1 more
core   +1 more source

Unveiling novel insights in prostate cancer through single-cell RNA sequencing

open access: yesFrontiers in Oncology, 2023
Single-cell RNA sequencing (scRNA-seq) is a cutting-edge technology that provides insights at the individual cell level. In contrast to traditional bulk RNA-seq, which captures gene expression at an average level and may overlook important details, scRNA-
Wenyue Yu   +3 more
doaj   +1 more source

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