Results 181 to 190 of about 3,688,571 (346)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Cell-cell interactions as predictive and prognostic markers for drug responses in cancer. [PDF]

Genome Med
Lu X, Tan X, Kim EJ, Jin X, Donovan ML, Cruz JLG, Xiong Z, de Los Reyes Becerra Perez MRB, Gong J, Monkman J, Agrawal D, Kulasinghe A, U. Q. CellOmics Innovation Forum, Nguyen Q, Tuong ZK.   +14 more
europepmc   +1 more source

Glycolipid recognition and binding by Siglec-6 hinges on interactions with the cell membrane

D'Andrea, Silvia
openalex   +1 more source

Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation

, 2005
Simona Parrinello, Jean‐Philippe Coppé, Ana Krtolica, Judith Campisi   +3 more
openalex   +2 more sources

CANCER: GENE INTERACTION AND CELL SIGNALLING

, 2022
Sumaiya Hasnain
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Quantitative Microscopy for Cell-Surface and Cell-Cell Interactions in Immunology. [PDF]

Bio Protoc
Díaz-Bello B, Arawi DE, Torro R, Chames P, Sengupta K, Limozin L.   +5 more
europepmc   +1 more source

Peroxisome Remnants in pex3Δ Cells and the Requirement of Pex3p for Interactions Between the Peroxisomal Docking and Translocation Subcomplexes [PDF]

, 2002
Partha Hazra, Ivet Suriapranata, William B. Snyder, Suresh Subramani   +3 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Extracellular Vesicles and B Cell Interactions: B-Side Track or Greatest Hit? [PDF]

ACS Nano
Troyer Z, Gololobova O, Driedonks TAP, Erickson LD, Wolfram J, Witwer KW.   +5 more
europepmc   +1 more source