Results 221 to 230 of about 679,265 (269)

Mycobacterial Invasion of Epithelial Cells

2000
Infections caused by organisms of the genera mycobacteria are responsible for a great percentage of yearly deaths dues to infectious diseases. Tuberculosis is a widespread infection caused by Mycobacterium tuberculosis. It is transmitted mainly as an airborne infection. M.
L E, Bermudez, F J, Sangari
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Vinculin, cell mechanics and tumour cell invasion

Cell Biology International, 2013
AbstractThe focal adhesion protein, vinculin, is important for transmitting mechanical forces and orchestrating mechanical signalling events. Deregulation of vinculin results in altered cell adhesion, contractility, motility and growth, all of which are important processes in cancer metastasis.
Wolfgang H, Goldmann, Vera, Auernheimer, Ingo, Thievessen, Ben, Fabry   +3 more
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Cell Migration and Invasion Assays

2011
A number of in vitro assays have been developed to study tumor cell motility. Historically, assays have been mainly monocellular, where carcinoma cells are studied in isolation. Scratch assays can be used to study the collective and directional movement of populations of cells, whereas two chamber assays lend themselves to the analysis of chemotactic ...
Moutasim, Karwan A., Nystrom, Maria L., Thomas, Gareth J.   +2 more
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Mechanisms of glioma cell invasion

2003
Invasive growth is one of the characteristics of gliomas--local infiltration into the surrounding nerve tissue decisively restricts all treatment strategies. Particularly the merit of all local treatment modalities is queried. The question whether a glioma represents a diffuse disease of the CNS or a local disturbance with unrestrained expansion ...
J C, Tonn, R, Goldbrunner
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Invasive squamous cell carcinoma of the conjunctiva

Plastic and Reconstructive Surgery, 1975
In cases of invasive conjunctival squamous cell carcinoma, three cases of deep corneal invasion and two cases of intraocular extension were found. Four cases showed orbital invasion, and one patient died of generalized metastases 18 months after diagnosis. The relatively low-grade nature of these lesions and their potential for local treatment is noted,
W J, Iliff, R, Marback, W R, Green
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Intravital Imaging and Cell Invasion

2007
The main cause of cancer treatment failure is the invasion of normal tissues by cancer cells that have migrated from a primary tumor. An important obstacle to understanding cancer invasion has been the inability to acquire detailed, direct observations of the process over time in a living system.
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Cell-cell adhesion in invasion and metastasis of carcinomas

1994
Metastasis of tumor cells involves a series of consecutive attachment and deattachment events that are based on a multitude of specific cell-to-cell and cell-to-substrate interactions. The process is initiated by disaggregation of invasive cells from the primary carcinoma — a step that requires a breakdown of intercellular adhesion (see below for a ...
J, Behrens, W, Birchmeier
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Tumor Cell Invasion Assays

2004
The ability of tumor cells to invade is one of the hallmarks of the metastatic phenotype. To elucidate the mechanisms by which tumor cells acquire an invasive phenotype, in vitro assays have been developed that mimic the in vivo process. The most commonly used in vitro invasion assay is a modified Boyden chamber assay using a basement membrane matrix ...
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Signaling Determinants of Glioma Cell Invasion

2012
Tumor cell invasiveness is a critical challenge in the clinical management of glioma patients. In addition, there is accumulating evidence that current therapeutic modalities, including anti-angiogenic therapy and radiotherapy, can enhance glioma invasiveness.
Aneta, Kwiatkowska, Marc, Symons
openaire   +3 more sources

Mechanisms of cancer cell invasion

Current Opinion in Genetics & Development, 2005
The movement of cancer cells into tissue surrounding the tumour and the vasculature is the first step in the spread of metastatic cancers. Recent advances in imaging, the use of 3D model systems and the application of microarray technologies have yielded new insights into these processes.
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