Results 241 to 250 of about 1,625,980 (311)

Confronting Upside-Down Video-Assisted Thoracic Surgery for Anterior Mediastinal Leiomyoma. [PDF]

Surg Case Rep
Takeuchi Y, Oki T, Iizuka S, Otsuki Y, Nakamura T.   +4 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Ultrarapid BRAF mutation detection on supernatant cell-free DNA obtained by FNA: An accurate and expedient method for BRAF assessment in aggressive thyroid carcinomas. [PDF]

Cancer Cytopathol
Gutierrez Amezcua JM, Arcila ME, Ng DL, Feratovic R, Bilal KH, Cohen JM, Wei XJ, Kezlarian-Sachs B, Sigel CS, Agaram N, Nafa K, Salazar P, Lin O, Kim D.   +13 more
europepmc   +1 more source

Remarkable Recovery After Delayed High‐Dose Methylprednisolone in a Rare Case of Penetrating Spinal Cord Injury

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Traumatic spinal cord injury (TSCI) caused by sharp‐force penetration is exceptionally rare, and the use of high‐dose methylprednisolone (MP) remains highly controversial, especially beyond the conventional 8‐h treatment window. This case report describes a 30‐year‐old male with acute incomplete TSCI following a knife stab wound to the right ...
Honghong Wang, Shuang Liu, Jiale Wang, Kaiyang Xue, Shenwei Li, Zhongheng Du   +5 more
wiley   +1 more source

Tumor Suppressor p53 and MicroRNAs Interaction in Breast Cancer. [PDF]

Oncol Res
Luna MEV, Lourenço GJ, Carron J.
europepmc   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Limited expression of B-cell maturation antigen in acute myeloid leukemia. [PDF]

J Immunother Cancer
Ran Y, Cheng W, Yi X, Yang S, Zhang W, Xu J.   +5 more
europepmc   +1 more source

PIK3CA mutant cervical cancer is selectively suppressed by PI3Kα inhibition (Alpelisib/BYL-719 and Inavolisib/GDC-0077) and cooperates with HPV directed T cell therapy. [PDF]

Neoplasia
Lou H, Langan D, Syracuse N, Murphy EA, Kim S, Robinson E, Rossi NM, Xie Y, Tulsyan S, Joe T, Rodriguez I, Rao N, Oberley MR, Oelke M, Dean M.   +14 more
europepmc   +1 more source

Quantifying the Dual Effect of Antitumor and Pro-Tumor Human Neutrophils on Natural Killer Cell Behaviors in a Microphysiological System. [PDF]

ACS Biomater Sci Eng
Shao S, Jones CN.
europepmc   +1 more source

Shaping next decade of systemic therapy for head and neck squamous cell carcinoma: where do we go next? [PDF]

Front Oncol
Saerens M, Vermassen T, Stevenheydens J, Lybaert W.   +3 more
europepmc   +1 more source