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Activity of Sulfonium Bisphosphonates on Tumor Cell Lines
Journal of Medicinal Chemistry, 2007We investigated three series of sulfonium bisphosphonates for their activity in inhibiting the growth of three human tumor cell lines. The first series consisted of 6 cyclic sulfonium bisphosphonates, the most active species having an (average) IC50 of 89 microM.
Yonghui, Zhang +7 more
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Development of tumor cell lines
Cancer Genetics and Cytogenetics, 1986A number of techniques are now in use in attempting to establish cell lines from human solid tumors. Although short-term cultures are readily attained, relatively few become established as permanent cell lines, especially from primary carcinomas where metastasis has not already occurred and from such organs as the breast, prostate, and pancreas.
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Resistance of human tumor cell lines to antifolates
Cancer Treatment Reviews, 1984Folate antagonists have over the last 30 years become increasingly important in the treatment of human cancer ( 18). However, only one of these agents, Methotrexate (MTX), can be considered as established in clinical use. Its use in chemotherapy of solid tumors and in maintenance therapy of lymphoblastic leukemia is widespread (12).
H, Diddens, D, Niethammer, R C, Jackson
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Human pituitary tumors with two cell lines
Archives of Oto-Rhino-Laryngology, 1983From the total material of 47 pituitary tumors, 42 had one cell line and five had two cell lines. The latter were found in tumors causing acromegaly either with secretion of growth hormone (GH) alone (n = 2) or in combination with prolactin (PRL) (n = 3).
M, Anniko, B, Tribukait, J, Wersäll
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Cytostasis of tumor cell lines by human granulocytes
Cellular Immunology, 1980Abstract Purified peripheral blood granulocytes from normal adult donors were tested for cytolytic and cytostatic activity against a variety of tumor-derived, virus-transformed, and normal cell lines. Altogether, 45 donors and 16 cell lines were tested.
S, Korec +3 more
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Selective distribution of fibronectin to a tumor-cell line
Cancer Letters, 1986Distribution of plasma fibronectin in Yoshida sarcoma-bearing rats was studied. Fibronectin from human plasma labelled with 125I was administered intravenously to the tumor bearing-rats. The ratios of specific radioactivity (cpm/g) of the tumor to that of blood or liver increased in the time course after the administration.
Y, Ueda +5 more
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Natural killer cell lines in tumor immunotherapy
Frontiers of Medicine, 2012Natural killer (NK) cells are considered to be critical players in anticancer immunity. However, cancers are able to develop mechanisms to escape NK cell attack or to induce defective NK cells. Current NK cell-based cancer immunotherapy is aimed at overcoming NK cell paralysis through several potential approaches, including activating autologous NK ...
Min, Cheng +4 more
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Antitumor Activities of Ellagitannins on Tumor Cell Lines
1999Recent phytochemical studies on tannins and related polyphenols in medicinal plants traditionally used in China, Japan, and other countries have led to the characterization of numerous hydrolyzable tannins with diverse structures and have enabled studies on biological activities of individual tannins of defined structure.1 The pharmacological ...
L L, Yang +5 more
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Production of interferon by human tumor cell lines
Archives of Virology, 1979Fourteen continuous human cell lines, including nine derived from tumors and five from non-neoplastic tissues, produced interferon in response to induction with bluetongue virus (BTV), Newcastle disease virus (NDV), and poly(I) . poly(C) complexed with DEAE-dextran.
P, Jameson, S E, Grossberg
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Nestin expression in human tumors and tumor cell lines.
Neoplasma, 2010The aim of this review is to summarize current knowledge on nestin expression in human tumors and corresponding tumor cell lines. Nestin belongs to class VI of the intermediate filaments and it is expressed primarily in mammalian nervous tissue during embryonic development. In adults, nestin occurs only in a small subset of cells and tissues.
O, Krupkova +3 more
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