Results 261 to 270 of about 1,625,980 (311)

Tumor-associated antigen from a human breast tumor cell line

Clinical Immunology and Immunopathology, 1982
Abstract Membrane-bound antigens were solubilized and purified from the continuously growing human mammary adenocarinoma cell line SW527. Two distinct breast tumor-associated antigens (BTA-1 and BTA-2) were obtained, as well as purified HLA antigens.
M, Kamiyama, G A, Hashim, H H, Fudenberg, O D, Holton, R E, Lovins   +4 more
openaire   +2 more sources

Tumor type‐specific differences in cell‐substrate adhesion among human tumor cell lines

International Journal of Cancer, 1987
AbstractCell lines derived from human tumors of 4 different histological types (squamous carcinomas, melanomas, gliomas and a fibrosarcoma) were examined for cell‐substrate adhesion on plastic culture dishes and dishes coated with 50 μg of type‐IV collagen.
J, Varani, T E, Carey, S E, Fligiel, P E, McKeever, V, Dixit   +4 more
openaire   +2 more sources

Four new human germ cell tumor cell lines.

Laboratory investigation; a journal of technical methods and pathology, 1988
Four new human tumor cell lines, NCC-EC-1, NCC-EC-2, NCC-EC-3, and NCC-IT, were derived from different germ cell tumors established in vitro. On the basis of morphologic studies of cell cultures and nude mice xenografts, it was concluded that NCC-EC-1, and NCC-EC-2 cell lines are equivalent to developmentally nullipotent embryonal carcinoma; cell line ...
S, Teshima, Y, Shimosato, S, Hirohashi, Y, Tome, I, Hayashi, H, Kanazawa, T, Kakizoe   +6 more
openaire   +2 more sources

Pediatric brain tumor cell lines.

Journal of cellular biochemistry, 2015
Pediatric brain tumors as a group, including medulloblastomas, gliomas, and atypical teratoid rhabdoid tumors (ATRT) are the most common solid tumors in children and the leading cause of death from childhood cancer. Brain tumor-derived cell lines are critical for studying the biology of pediatric brain tumors and can be useful for initial screening of ...
Jingying, Xu, Ashley, Margol, Shahab, Asgharzadeh, Anat, Erdreich-Epstein   +3 more
openaire   +1 more source

Activity of Sulfonium Bisphosphonates on Tumor Cell Lines

Journal of Medicinal Chemistry, 2007
We investigated three series of sulfonium bisphosphonates for their activity in inhibiting the growth of three human tumor cell lines. The first series consisted of 6 cyclic sulfonium bisphosphonates, the most active species having an (average) IC50 of 89 microM.
Yonghui, Zhang, Michael P, Hudock, Kilannin, Krysiak, Rong, Cao, Kyle, Bergan, Fenglin, Yin, Annette, Leon, Eric, Oldfield   +7 more
openaire   +2 more sources

Drug resistance in malignant rhabdoid tumor cell lines

Cancer Chemotherapy and Pharmacology, 2001
We evaluated the in vitro sensitivity of four malignant rhabdoid tumor (MRT) cell lines to six chemotherapeutic agents: 5-fluororuacil, vincristine, carboplatin, doxorubicin, etoposide, and paclitaxel. We also sought to determine whether a defect in the p53 signaling pathway may contribute to the pronounced drug resistance of MRT.MRT cells were treated
Gary B, Rosson, Timothy S, Vincent, Betty W, Oswald, Cynthia F, Wright   +3 more
openaire   +2 more sources

Migratory potential of transplantable neural tumor cell lines

Acta Neuropathologica, 1999
Experimentally induced primitive neuroectodermal tumor (PNET) cell lines were transplanted into neonatal and adult rat brain and examined neuropathologically for their tumorigenic potential. Both cell lines showed a striking migratory behavior in both neonatal and adult brain.
T A, Bayer, M, Thier, E, Roeb, B, Breuer, S, Weggen, O D, Wiestler, J, Weis   +6 more
openaire   +2 more sources

First-Line Chemotherapy of Disseminated Germ Cell Tumors

Hematology/Oncology Clinics of North America, 2011
The development of effective chemotherapy has been the defining event in the history of testicular cancer treatment. The discovery of cisplatin-based chemotherapy created a massive inflection that sharply defined the relatively grim precisplatin era from the astonishing postcisplatin era.
Craig, Nichols, Christian, Kollmannsberger   +1 more
openaire   +2 more sources

Resistance of human tumor cell lines to antifolates

Cancer Treatment Reviews, 1984
Folate antagonists have over the last 30 years become increasingly important in the treatment of human cancer ( 18). However, only one of these agents, Methotrexate (MTX), can be considered as established in clinical use. Its use in chemotherapy of solid tumors and in maintenance therapy of lymphoblastic leukemia is widespread (12).
H, Diddens, D, Niethammer, R C, Jackson
openaire   +2 more sources

Cytostasis of tumor cell lines by human granulocytes

Cellular Immunology, 1980
Abstract Purified peripheral blood granulocytes from normal adult donors were tested for cytolytic and cytostatic activity against a variety of tumor-derived, virus-transformed, and normal cell lines. Altogether, 45 donors and 16 cell lines were tested.
S, Korec, R B, Herberman, J H, Dean, G B, Cannon   +3 more
openaire   +2 more sources