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dbl Oncogene Expression in Childhood Tumors and Tumor Cell Lines
Diagnostic Molecular Pathology, 1993We studied the expression of the dbl oncogene in the total RNA obtained from a wide spectrum of childhood tumors, including Ewing's sarcomas, peripheral neuroectodermal tumors (PNET), esthesioneuroblastomas, neuroblastomas, retinoblastomas, rhabdomyosarcomas, osteosarcomas, and synovial sarcomas.
S, Navarro +6 more
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Activity of Sulfonium Bisphosphonates on Tumor Cell Lines
Journal of Medicinal Chemistry, 2007We investigated three series of sulfonium bisphosphonates for their activity in inhibiting the growth of three human tumor cell lines. The first series consisted of 6 cyclic sulfonium bisphosphonates, the most active species having an (average) IC50 of 89 microM.
Yonghui, Zhang +7 more
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Establishment of Tumor Cell Lines: From Primary Tumor Cells to a Tumor Cell Line
2018Adequate cell lines and cell systems are the cornerstone of various research fields, with the aim of reflecting the tissue of origin as closely as possible in order to obtain optimal research conditions. Cell lines are defined as continuously growing cell cultures, with unlimited proliferation.
Katharina Meditz, Beate Rinner
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Azithromycin as Potent Inhibitor of Cell Migration in Tumor Cell Line
Journal of Hunan University Natural Sciences, 2022Continuous obstacles behind the discovery of novel drugs for cancer therapy have necessitated the development of alternative strategy of drug repurposing—the development of old drugs for new therapeutic purposes. With an improved understanding of the hallmarks of cancer, this strategy offers a cost-effective process for the treatment of human ...
Shumaila Usman +6 more
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Development of tumor cell lines
Cancer Genetics and Cytogenetics, 1986A number of techniques are now in use in attempting to establish cell lines from human solid tumors. Although short-term cultures are readily attained, relatively few become established as permanent cell lines, especially from primary carcinomas where metastasis has not already occurred and from such organs as the breast, prostate, and pancreas.
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Natural killer cell lines in tumor immunotherapy
Frontiers of Medicine, 2012Natural killer (NK) cells are considered to be critical players in anticancer immunity. However, cancers are able to develop mechanisms to escape NK cell attack or to induce defective NK cells. Current NK cell-based cancer immunotherapy is aimed at overcoming NK cell paralysis through several potential approaches, including activating autologous NK ...
Min, Cheng +4 more
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Resistance of human tumor cell lines to antifolates
Cancer Treatment Reviews, 1984Folate antagonists have over the last 30 years become increasingly important in the treatment of human cancer ( 18). However, only one of these agents, Methotrexate (MTX), can be considered as established in clinical use. Its use in chemotherapy of solid tumors and in maintenance therapy of lymphoblastic leukemia is widespread (12).
H, Diddens, D, Niethammer, R C, Jackson
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Production of interferon by human tumor cell lines
Archives of Virology, 1979Fourteen continuous human cell lines, including nine derived from tumors and five from non-neoplastic tissues, produced interferon in response to induction with bluetongue virus (BTV), Newcastle disease virus (NDV), and poly(I) . poly(C) complexed with DEAE-dextran.
P, Jameson, S E, Grossberg
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