Cell division promotes efficient retrotransposition in a stable L1 reporter cell line [PDF]
Background: Long interspersed element type one (L1) actively modifies the human genome by inserting new copies of itself. This process, termed retrotransposition, requires the formation of an L1 ribonucleoprotein (RNP) complex, which must enter the ...
Ivics, Z. +17 more
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Generation of a human induced pluripotent stem cell line from a patient with Leber congenital amaurosis [PDF]
Leber congenital amaurosis (LCA) is an inherited retinal dystrophy that is characterized by severe visual impairment in early infancy. We generated a human induced pluripotent stem cell (hiPSC) line, DKHi090-A, from peripheral blood mononuclear cells ...
한진우
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Establishment and characterization of a human papillary thyroid carcinoma cell line with oxyphilic differentiation (ONCO-DG 1) [PDF]
In the present study the establishment and characterization of a new oxyphilic papillary thyroid carcinoma cell line--ONCO-DG1- is given. With immunohistological, histochemical and flow cytometric methods, ONCO-DG 1 cells revealed features of epithelial ...
Grimm, Daniela +13 more
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The FAM deubiquitylating enzyme localizes to multiple points of protein trafficking in epithelia, where it associates with E-cadherin and beta-catenin [PDF]
Copyright © 2004 by The American Society for Cell Biology.Ubiquitylation is a necessary step in the endocytosis and lysosomal trafficking of many plasma membrane proteins and can also influence protein trafficking in the biosynthetic pathway.
Murray, Rachael +8 more
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A cell line derived from BBN (N-butyl-N-[4-hydroxybutyl]-nitrosamine)-induced rat bladder cancer: establishment and scanning electron microscopic cell surface characteristics [PDF]
This research was performed to establish a cell line from experimental bladder tumor and to discuss the biological characteristics of the cell line so established. Tissue cultures of epithelial cells were derived from a rat bladder cancer induced by BBN.
Nishi, Mitsuo
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Reaction–Diffusion Finite Element Model of Lateral Line Primordium Migration to Explore Cell Leadership [PDF]
Collective cell migration plays a fundamental role in many biological phenomena such as immune response, embryogenesis and tumorigenesis. In the present work, we propose a reaction–diffusion finite element model of the lateral line primordium migration ...
ALLENA, Rachele, MAINI, Philip
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Human cell line (HGC-27) derived from the metastatic lymph node of gastric cancer [PDF]
A cell line (HGC-27) was established by culture of the metastatic lymph node from a gastric cancer patient diagnosed histologically as undifferentiated carcinoma.
Kimoto, Tetsuo, Akagi, Tadaatsu
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The correlation of keratin expression with in-vitro epithelial cell line differentiation [PDF]
MPhil 2009 QMThe mechanism of transcriptional regulation which allows oral mucosal-specific expression of the human keratin 13 (K13) gene remains unknown.
Aden, Deeqo
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A reference human induced pluripotent stem cell line for large-scale collaborative studies [PDF]
Human induced pluripotent stem cell (iPSC) lines are a powerful tool for studying development and disease, but the considerable phenotypic variation between lines makes it challenging to replicate key findings and integrate data across research groups ...
Basundra, Richa +177 more
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Ductal Ngn3-expressing progenitors contribute to adult β cell neogenesis in the pancreas
Ductal cells have been proposed as a source of adult β cell neogenesis, but this has remained controversial. By combining lineage tracing, 3D imaging, and single-cell RNA sequencing (scRNA-seq) approaches, we show that ductal cells contribute to the β ...
Rackham, Chloe +29 more
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