Results 41 to 50 of about 11,546,320 (306)

Generation of an iPSC line from a retinitis pigmentosa patient carrying a homozygous mutation in CERKL and a healthy sibling

Stem Cell Research, 2019
Dermal fibroblasts from an autosomal recessive retinitis pigmentosa (RP) patient, homozygous for the mutation c.769 C>T, p.Arg257Ter, in CERKL (Ceramide Kinase-Like) gene, and a healthy sibling were derived and reprogrammed by Sendai virus. The generated
Arantxa Bolinches-Amorós, Marian León, Verónica del Buey Furió, Gemma Marfany, Roser Gonzàlez-Duarte, Slaven Erceg, Dunja Lukovic   +6 more
doaj   +1 more source

Establishment of A Novel Paclitaxel-Resistant Triple-Negative Breast Cancer Cell Line

Journal of Health Science and Medical Research (JHSMR), 2023
Objective: Triple-negative breast cancer (TNBC) is one of the most aggressive subtypes of breast cancer, and is associated with poor prognosis. Paclitaxel, a microtubule-binding agent, and chemotherapeutic agent, has been widely used in the management of
Thanaporn Khunpitak, Pasarat Khongkow
doaj   +1 more source

Mir-129-2-3p Has Tumor Suppressor Role in Ewing Sarcoma Cell Lines and Cancer Tissue Samples

Brazilian Archives of Biology and Technology, 2021
Deregulation of miRNA expressions was identified as a novel feature of tumor biology in Ewing sarcoma (EWS). The aim was to evaluate the regulatory role of miR-129-2-3p in EWS cell lines and human EWS tissue samples.
Esra Guzel Tanoglu, Yavuz Arıkan, Yavuz Selim Kabukcuoglu, Fevziye Kabukcuoglu, Alpaslan Tanoglu, Sukru Ozturk   +5 more
doaj   +1 more source

Do-it-yourself instrument integration into an existing mammalian cell line development automation platform

SLAS Technology
Laboratory automation in the biopharmaceutical industry as a rule requires contracted service from highly professional automation solution provider, at times involving the purchase and development of specialized or customized hardware and software, which
Jie Ding, Kee Wee Tan, Xiaoyue Chen
doaj   +1 more source

Human surfactant protein D alters oxidative stress and HMGA1 expression to induce p53 apoptotic pathway in eosinophil leukemic cell line [PDF]

, 2013
This article is made available through the Brunel Open Access Publishing Fund. Copyright: © 2013 Mahajan et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use ...
Pandit Hrishikesh, Uday Kishore (504246), Ravi Sirdeshmukh, P. Usha Sarma (504245), Curam S Sundaram, Lakshna Mahajan (504239), Madan, T, Ajit K Yadav, Madan Taruna, Poonam Gautam, Ajit K. Yadav (504242), Curam S. Sundaram (504244), Yadav Ajit K., Ravi Sirdeshmukh (131378), Himangi Warke, P. Usha Sarma, Surolia Avadhesha, Warke Himangi, Lakshna Mahajan, Hrishikesh Pandit, Pandit, H, Sundaram, CS, Himangi Warke (504243), Sarma, PU, Poonam Gautam (131332), Sundaram Curam S., Sirdeshmukh Ravi, Sarma P. Usha, Surolia, A, Curam S. Sundaram, Avadhesha Surolia (78297), Mahajan, L, Kishore Uday, Yadav, AK, Sirdeshmukh, R, Warke, H, Taruna Madan, Kishore, U, Taruna Madan (504241), P Usha Sarma, Gautam, P, Mahajan Lakshna, Gautam Poonam, Hrishikesh Pandit (504240), Ajit K. Yadav, Avadhesha Surolia, Uday Kishore   +46 more
core   +2 more sources

Impact of progesterone on innate immunity and cell death after influenza A virus H1N1 2009 infection of lung and placental cells in vitro

Frontiers in Virology, 2022
The influenza A virus (IAV) 2009 H1N1 pandemic was associated with an increased risk of maternal mortality, preterm birth, and stillbirth. The underlying mechanism for severe maternal lung disease and stillbirth is incompletely understood, but IAV ...
Miranda Li, Miranda Li, Amanda Li, Amanda Li, Hazel Huang, Jeff Munson, Adebimpe Obadan, Deborah H. Fuller, Kristina M. Adams Waldorf, Kristina M. Adams Waldorf   +9 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Role of p52 (NF-κB2) in LPS tolerance in a human B cell line [PDF]

, 1999
Cells of the weakly CD14 positive human B cell line RPMI 8226, clone 1, will mobilize NF-κB (p50/p65 and p50/p50) proteins and produce TNF mRNA when stimulated with lipopolysaccharide (LPS), When such cells are precultured with a low amount of LPS (50 ...
Wedel, Angela, Sulski, Gabi, Kuprash, Dmitry, H.W. Loems Ziegler-Heitbrock, Angela Wedel, Marion Frankenberger, Irmhild Petersmann, Nedospasov, Sergei, Frankenberger, Marion, Petersmann, Irmhild, Ziegler-Heitbrock, H. W. Loems, Dmitry Kuprash, Sergei Nedospasov, Gabi Sulski   +13 more
core   +1 more source

Utility of a Large Series of B‐Cell Precursor Acute Lymphoblastic Leukemia Cell Lines as a Model System

Cancer Medicine
Background In B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL), chromosomal translocations are strongly associated with prognoses. RNA sequencing (RNA‐seq) is a powerful technology that reveals a close correlation between types of translocation ...
Minori Tamai, Chiaki Komatsu, Keiko Kagami, Shin Kasai, Koshi Akahane, Kumiko Goi, Kanji Sugita, Chihiro Tomoyasu, Toshihiko Imamura, Hiroaki Goto, Takeshi Inukai   +10 more
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source