Results 71 to 80 of about 18,536,823 (334)

Establishment and characterization of mouse metabolic dysfunction-associated steatohepatitis-related hepatocellular carcinoma organoids

Scientific Reports
Metabolic dysfunction-associated steatohepatitis (MASH) is a form of chronic liver inflammation associated with metabolic syndrome, such as obesity and a major cause of hepatocellular carcinoma (HCC).
Sumin Kim, Nahyun Jeong, Jeayeon Park, Hyojin Noh, Ja Oh Lee, Su Jong Yu, Ja-Lok Ku   +6 more
doaj   +1 more source

In Vitro Transfection of Up-Regulated Genes Identified in Favorable-Outcome Neuroblastoma into Cell Lines

Cells, 2022
We previously used microarrays to show that high expression of DHRS3, NROB1, and CYP26A1 predicts favorable NB outcomes. Here, we investigated whether expression of these genes was associated with suppression of NB cell (SK-N-SH, NB12, and TGW) growth ...
Yoko Hiyama, Emi Yamaoka, Takahiro Fukazawa, Masato Kojima, Yusuke Sotomaru, Eiso Hiyama   +5 more
doaj   +1 more source

Cell patterning on photolithographically defined parylene-C:SiO2 substrates [PDF]

, 2014
Cell patterning platforms support broad research goals, such as construction of predefined in vitro neuronal networks and the exploration of certain central aspects of cellular physiology.
Brennan, Paul M, Bunting, Andrew S, Hughes, Mark A, Murray, Alan F, Shipston, Mike J   +4 more
core   +2 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Effects of simulated microgravity on colorectal cancer organoids growth and drug response

Scientific Reports
Cellular and molecular dynamics of human cells are constantly affected by gravity. Alteration of the gravitational force disturbs the cellular equilibrium, which might modify physiological and molecular characteristics. Nevertheless, biological responses
Soon-Chan Kim, Min Jung Kim, Ji Won Park, Young-Kyoung Shin, Seung-Yong Jeong, Sungwan Kim, Ja-Lok Ku   +6 more
doaj   +1 more source

Establishment of a gastric cancer cell line with high microsatellite instability, OCUM‐13, derived from Borrmann type‐2 primary tumor

Cancer Medicine, 2023
Gastric cancer (GC) with microsatellite instability (MSI) has been reported to be sensitive to immunotherapy, however some of GC cases with MSI remain resistant to immunotherapy.
Yurie Yamamoto, Go Masuda, Shuhei Kushiyama, Koji Maruo, Gen Tsujio, Tomohiro Sera, Atsushi Sugimoto, Sadaaki Nishimura, Kenji Kuroda, Shingo Togano, Tomohisa Okuno, Masaichi Ohira, Masakazu Yashiro   +12 more
doaj   +1 more source

In Vitro Infection Dynamics of Wuxiang Virus in Different Cell Lines

Viruses, 2022
Wuxiang virus (WUXV) is a newly discovered Bunyavirales transmitted by sandflies. It is found to infect humans and chickens and can cause neurological symptoms and even death in mice.
Xiaohui Yao, Qikai Yin, Danhe Hu, Shihong Fu, Weijia Zhang, Kai Nie, Fan Li, Songtao Xu, Ying He, Guodong Liang, Xiangdong Li, Huanyu Wang   +11 more
doaj   +1 more source

Design of Dual-band Branch-Line Coupler Based on Shunt Open-Circuit DCRLH Cells [PDF]

, 2013
In this article, the shunt open-circuit dual composite right/left-handed (DCRLH) cell is initially proposed and one dual-band branch-line coupler based on the proposed cells is designed.
Bo Tian, Guang-Ming Wang, Ke Lu
core  

Cytosolic delivery of nanolabels prevents their asymmetric inheritance and enables extended quantitative in vivo cell imaging [PDF]

, 2016
Long-term in vivo imaging of cells is crucial for the understanding of cellular fate in biological processes in cancer research, immunology, or in cell-based therapies such as beta cell transplantation, in type I diabetes or stem cell therapy ...
Braeckmans, Kevin, De Rycke, Riet, De Smedt, Stefaan, Demeester, Jo, Himmelreich, Uwe, Joris, Freya, Liang, Sayuan, Lippens, Saskia, Raemdonck, Koen, Skirtach, Andre, Xiong, Ranhua   +10 more
core   +7 more sources

Duplex DNA from Sites of Helicase-Polymerase Uncoupling Links Non-B DNA Structure Formation to Replicative Stress [PDF]

, 2020
BACKGROUND: Replication impediments can produce helicase-polymerase uncoupling allowing lagging strand synthesis to continue for as much as 6 kb from the site of the impediment.
Abdelhamid, Mahmoud A S, Amparo, Camille, Bedell, Victoria, Clark, Jarrod, Martella, Marianna, Murata-Collins, Joyce L, Pichiorri, Flavia, Smith, Steven S, Waller, Zoë A E, Warner, Emily F   +9 more
core   +2 more sources