Results 201 to 210 of about 11,198,861 (420)

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

Advanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang, Zizhang Li, Jingyu Chen, Wenjing Yang, Xingxing He, Peng Wu, Feng Chen, Ziwei Zhou, Chenze Ren, Yuyan Shan, Xiewen Wen, Vassily A. Lyubetsky, Leonid Yu. Rusin, Xiaoshu Chen, Jian‐Rong Yang   +14 more
wiley   +1 more source

Discrete stages of human intrathymic differentiation: Analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage

, 1980
Ellis L. Reinherz, Patrick C. Kung, Gideon Goldstein, Raphael H. Levey, Stuart F. Schlossman   +4 more
openalex   +1 more source

Presence of a p70 IL-2-binding peptide on leukemic cells from various hemopoietic lineages. [PDF]

, 1989
M Allouche, Yasmina Sahraoui, Yvette Augery-Bourget, Yuji Ohashi, Kazuo Sugamura, C Jasmin, Vassilis Georgoulias   +6 more
openalex   +1 more source

AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells

Advanced Science, EarlyView.
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu, Guisheng Chen, Rui Hu, Peiwen Liu, Jintao Lou, Wenji Zhao, Zuhong He, Suhua Sha, Yiqing Zheng   +8 more
wiley   +1 more source

Multi-lineage ‘stem’ cells in the mammalian embryo

, 1988
R. L. Gardner, R. S. P. Beddington
openalex   +1 more source

Development of a cell with dendritic morphology from a precursor of B lymphocyte lineage. [PDF]

, 1987
M. P. Corradi, Diane F. Jelinek, Jane E. Ramberg, Peter E. Lipsky   +3 more
openalex   +1 more source

The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges

Advanced Science, EarlyView.
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li, Ying Zhang, Zhenyu Xiao, Jieyu Qi   +3 more
wiley   +1 more source

Cross-lineage gene rearrangements in human leukemic B-precursor cells occur frequently with V-DJ rearrangements of IgH genes [PDF]

, 1989
Tetsuya Nosaka, K Kita, H Miwa, Keiki Kawakami, Toshio Ikeda, Toshiyuki Ohno, Norihiro Matsuoka, Yuu Arita, S Doi, M Nishikori   +9 more
openalex   +1 more source

Accurate Transcription Factor Activity Inference to Decipher Cell Identity from Single‐Cell Transcriptomic Data with MetaTF

Advanced Science, EarlyView.
MetaTF is a new computational framework that uses single‐cell RNA sequencing (scRNA‐seq) data to infer transcription factor activity with the aim to help in deciphering cells identity starting from a heterogeneous population, and apply it to characterize mouse hematopoietic stem cells and breast cancer epithelial cells, thus identifying a novel subset ...
Yongfei Hu, Yuanyuan Zhu, Guangjue Tang, Ming Shan, Puwen Tan, Ying Yi, Xiyuan Zhang, Man Liu, Xinyu Li, Le Wu, Jia Chen, Hailong Zheng, Yan Huang, Zhuan Li, Xiaobo Li, Dong Wang   +15 more
wiley   +1 more source

Immunoglobulin and T-cell receptor beta-chain gene rearrangement analysis of Hodgkin's disease: implications for lineage determination and differential diagnosis.

, 1986
Dan Knowles, Antonino Neri, Pier Giuseppe Pelicci, Jerome S. Burke, Anna M. Wu, Carl D. Winberg, Khalil Sheibani, Riccardo Dalla‐Favera   +7 more
openalex   +1 more source