Force balance and membrane shedding at the Red Blood Cell surface
During the aging of the red-blood cell, or under conditions of extreme echinocytosis, membrane is shed from the cell plasma membrane in the form of nano-vesicles.
D. E. Discher+13 more
core +1 more source
Synthesis of extracellular matrix components by human ciliary muscle cells in culture [PDF]
The production and spatial organization of connective tissue components in ciliary muscle cell cultures was studied with immunohistochemical and ultrastructural methods.
Baur, A.+2 more
core +1 more source
Line tension at lipid phase boundaries as driving force for HIV fusion peptide-mediated fusion
HIV preferentially fuses with lipid membranes at the interface between ordered and disordered domains, but the mechanistic basis for this observation is not known. Here Yang et al.
Sung-Tae Yang+2 more
doaj +1 more source
The cell membrane forms an integral part of cellular homeostasis. This article will review the structure and function of physiological membranes and how the lipid bilayer plays an important role in maintaining cellular integrity, ion permeability, and membrane potential as well as being selectively permeable to certain biological substances.
openaire +3 more sources
Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair
The role of annexins in cell membrane repair is largely undefined. Here the authors use a model lipid bilayer to show that annexin A4 induces curvature at the membrane free edge and annexin A6 induces constriction force, and find that both annexins are ...
Theresa Louise Boye+7 more
doaj +1 more source
The Roles of Membrane Rafts in CD32A-Mediated Phagocytosis [PDF]
Membrane rafts are highly dynamic heterogeneous sterol- and sphingolipid-rich micro-domains on cell surfaces. They are generally believed to provide residency for cell surface molecules (e.g., adhesion and signaling molecules) and scaffolding to ...
Cheng Zhu+2 more
core +2 more sources
Oxidation of F-actin controls the terminal steps of cytokinesis
Cytokinetic abscission relies on the local constriction after cytoskeleton disassembly, but it is not known how the actin filaments are disassembled. Here, the authors show that the redox enzyme MICAL1 is recruited by Rab35 and induces oxidation-mediated
Stéphane Frémont+11 more
doaj +1 more source
Integrin-mediated membrane blebbing is dependent on the NHE1 and NCX1 activities. [PDF]
Integrin-mediated signal transduction and membrane blebbing have been well studied to modulate cell adhesion, spreading and migration^1-6^. However, the relationship between membrane blebbing and integrin signaling has not been explored.
Chi-Hung Lin+8 more
core +1 more source
Putative cell adhesion membrane protein Vstm5 regulates neuronal morphology and migration in the central nervous system [PDF]
During brain development, dynamic changes in neuronal membranes perform critical roles in neuronal morphogenesis and migration to create functional neural circuits.
Ko, Kwang Woo+5 more
core +2 more sources
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source